British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda +2 more
wiley +1 more source
The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers [PDF]
, 1992 A multicenter prospective trial was performed to investigate the efficacy and the tolerability of halofantrine in nonimmune patients with malaria imported from areas with drug-resistant falciparum parasites (mainly Africa).
Bock, H. L. +8 more
core +1 more source
Antimalarial Drugs-Induced Hepatic Injury in Rats and the Protective Role of Carnosine
Pharmaceutical Sciences, 2016 Background: Chloroquine and amodiaquine are used in the prophylaxis and treatment of malaria. However, hepatic injury is associated with malaria drug therapy. On the other hand, there is no promising hepatoprotective agent for prophylaxis or treatment of
Akram Jamshidzadeh, Reza Heidari, Farzaneh Abazari, Maral Ramezani, Forouzan Khodaei, Mohammad Mehdi Ommati, Maryam Ayarzadeh, Roya Firuzi, Arastoo Saeedi, Negar Azarpira, Asma Najibi
doaj +1 more source
Knowledge, attitudes and practices of malaria control among communities from the health district of Forécariah in the Republic of Guinea, West Africa. [PDF]
, 2014 BACKGROUND & OBJECTIVES: Malaria is the leading cause of death in children under 5-yr of age in the Republic of Guinea. This study aimed at investigating the knowledge, attitudes and practices of malaria control in urban and rural communities in Guinea ...
Banek, Kristin +3 more
core +1 more source
Temporal changes in haematocrit following artemisinin-based combination treatments of uncomplicated falciparum malaria in children [PDF]
, 2015 Semilog plots of deficit in haematocrit from 30Â % versus time in children with haematocrit
Adejumoke I. Ayede +6 more
core +4 more sources
Response to malaria epidemics in Africa. [PDF]
, 2007 Malaria epidemics affect nonimmune populations in many highland and semi-arid areas of Africa. Effective prevention of these epidemics is challenging, particularly in the highlands where predictive accuracy of indicators is not sufficiently high to allow
Abeku, Tarekegn A
core +3 more sources
Drugs in R&D, 2020 Background In 2006, the National Malaria Control Program in Mali recommended artemisinin-based combination therapy as the first-line treatment for uncomplicated malaria.
Karim Traoré +12 more
doaj +1 more source
Journal of Applied Sciences and Environmental Management, 2018 Cu (ll) and Co (II) complexes of amodiaquine hydrochloride and sulphamethazine (AMOSUF) have been prepared and characterized by elemental analysis, molar conductivity, FTIR and electronic spectroscopy.
E.A. Enemose, E.E. Akporhonor, B Kpomah
doaj +1 more source
Examination of effectiveness of chemical scavengers as therapeutics in organophosphate poisoning [PDF]
, 2017 Cholinergic crisis triggered by inhibition of cholinesterases via organophosphorus nerve agents (OP) and pesticides is treated with atropine and a reactivator of inhibited cholinesterase, called oxime.
Bierwisch, Anne
core
Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance [PDF]
, 2023 Mahamat Souleymane Issa +13 more
openalex +1 more source