Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine
Antimicrobial Agents and Chemotherapy, 2018 Across sub-Saharan Africa, patients with HIV on antiretrovirals often get malaria and need cotreatment with artemisinin-containing therapies. We undertook two pharmacokinetic studies in healthy volunteers, using standard adult doses of artemether ...
S. Walimbwa +11 more
semanticscholar +1 more source
High Efficacy of Two Artemisinin-Based Combinations (Artesunate + Amodiaquine and Artemether + Lumefantrine) in Caala, Central Angola. [PDF]
, 2006 In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Coartem) or artesunate + amodiaquine (ASAQ).
Balkan, S +10 more
core +1 more source
Early Changes in Plasmodium falciparum Asexual and Sexual Populations in Children with Acute Infections Following Treatment with Artemisinin-Based Combination Drugs [PDF]
, 2012 Artemisinin-based combination therapies (ACTs) may influence malaria transmission but the early changes in parasite populations have not been frequently evaluated.
Gbotosho, Grace O. +3 more
core +1 more source
Malaria Journal, 2018 Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that is established across mainland South-East Asia represents today a major threat to global health.
F. Grandesso +12 more
semanticscholar +1 more source
Decreased Prevalence of Plasmodium Falciparum Resistance Markers to Amodiaquine Despite its wide Scale use as ACT Partner Drug in Zanzibar. [PDF]
, 2012 Zanzibar has recently undergone a rapid decline in Plasmodium falciparum transmission following combined malaria control interventions with artemisinin-based combination therapy (ACT) and integrated vector control.
Björkman, Anders +7 more
core +4 more sources
Drugs in R&D, 2020 Background In 2006, the National Malaria Control Program in Mali recommended artemisinin-based combination therapy as the first-line treatment for uncomplicated malaria.
Karim Traoré +12 more
doaj +1 more source
Malaria Journal, 2018 Prompt, effective treatment of confirmed malaria cases with artemisinin-based combination therapy (ACT) is a cornerstone of malaria control. Maximizing adherence to ACT medicines is key to ensuring treatment effectiveness.
K. Banek +4 more
semanticscholar +1 more source
The Pharmacogenetics of the Antimalarial Amodiaquine
, 2012 Jose Pedro Gil1,2,3 1Department of Physiology and Pharmacology, Drug Resistance Unit, Division of Pharmacogenetics, Karolinska Institutet, Stockholm, 2Department of Biomedical Sciences, University of Algarve IBB-Institute for Biotechnology and Bioengineering, The Centre for Molecular and Structural Biomedicine, Gambelas, 3Department of Biological ...
openaire +4 more sources
Systematic review of amodiaquine treatment in uncomplicated malaria
The Lancet, 1996 Opinion and policy over the use of amodiaquine for treating malaria vary. Amodiaquine is more palatable than chloroquine and may be more effective but serious adverse events have been reported in travellers taking it as prophylaxis. It is not recommended as first-line treatment.
Olliaro P. +6 more
openaire +4 more sources
Degradation of Artemisinin-Based Combination Therapies Under Tropical Conditions. [PDF]
, 2016 Poor quality antimalarials, including falsified, substandard, and degraded drugs, are a serious health concern in malaria-endemic countries. Guidelines are lacking on how to distinguish between substandard and degraded drugs.
Allan, Elizabeth Louise +4 more
core +2 more sources