Results 141 to 150 of about 17,783 (291)

Preparation and evaluation of mixed-ligand complexes of Cu (II) and Co (II) with amodiaquine hydrochloride and sulphamethazine

Journal of Applied Sciences and Environmental Management, 2018
Cu (ll) and Co (II) complexes of amodiaquine hydrochloride and sulphamethazine (AMOSUF) have been prepared and characterized by elemental analysis, molar conductivity, FTIR and electronic spectroscopy.
E.A. Enemose, E.E. Akporhonor, B Kpomah
doaj   +1 more source

Efficacy of artesunate–amodiaquine in the treatment of falciparum uncomplicated malaria in Madagascar

Malaria Journal, 2018
Since 2006, the artemisinin-based combination therapy (ACT) are recommended to treat uncomplicated malaria including non Plasmodium falciparum malaria in Madagascar. Artesunate–amodiaquine (ASAQ) and artemether–lumefantrine are the first- and second-line
Oméga Raobela, V. Andriantsoanirina, David Gael Rajaonera, T. Rakotomanga, Stéphane Rabearimanana, Fanomezantsoa Ralinoro, D. Ménard, A. Ratsimbasoa   +7 more
semanticscholar   +1 more source

Quality of artemisinin-based combination formulations for malaria treatment: prevalence and risk factors for poor quality medicines in public facilities and private sector drug outlets in Enugu, Nigeria. [PDF]

, 2015
BACKGROUND: Artemisinin-based combination therapies are recommended by the World Health Organisation (WHO) as first-line treatment for Plasmodium falciparum malaria, yet medication must be of good quality for efficacious treatment. A recent meta-analysis
Allan, Elizabeth Louise, Clarke, Siân, Culzoni, Maria Julia, Dwivedi, Prabha, El Sherbiny, Mohamed, Fernández, Facundo M, Green, Michael D, Hall, Zoe, Ibe, Ogochukwu, Kaur, Harparkash, Mamadu, Ibrahim, Onwujekwe, Obinna, Schellenberg, David, Swamidoss, Isabel, van Wyk, Albert, Yeung, Shunmay   +15 more
core   +1 more source

Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso

Malaria Journal, 2008
Background Combination therapy has become a new paradigm in malaria treatment. Amodiaquine is a common partner drug in different malaria combination therapies used or investigated in sub-Saharan Africa, but data on its efficacy as a single drug are ...
Meissner Peter, Coulibaly Boubacar, Mockenhaupt Frank P, Mandi Germain, Müller Olaf   +4 more
doaj   +1 more source

EFFECT OF AMODIAQUINE ON GASTRIC HISTAMINE METHYLTRANSFERASE AND ON HISTAMINE‐STIMULATED GASTRIC SECRETION [PDF]

, 1975
H. Barth, W. Lorenz, H. Troidl
openalex   +1 more source

Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa

Infection, Genetics and Evolution, 2007
Despite the pharmacodynamic advantages with artemisinin-based combination therapy (ACT) and some potentially opposite molecular mechanisms of tolerance to amodiaquine (AQ)/desethylamodiaquine (DEAQ) and artesunate (ART), there is a risk for rapid decay in efficacy if the two drugs are unable to ensure mutual prevention against a selection and spread of
Gabrielle Holmgren, Johan Hamrin, José Pedro Gil, José Pedro Gil, Anders Björkman, Andreas Mårtensson, Jenny Svärd   +6 more
openaire   +3 more sources

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul, Andrews, Anishetty, Arama, Berman, Bernstein, Bhasin, Boeckmann, Chang, Chawley, Chen, Colovos, Corpet, David Charles Warhurst, Eisenberg, Finn, Franceschini, Ghosh, Irwin, Irwin, Kanehisa, Konc, Krogh, Kushwaha, Larsen, Laskowski, Ludin, Miller, Morris, Mrutyunjay Suar, Mulder, Pieper, Pierleoni, Pontius, Rajani Kanta Mahapatra, Sali, Subhashree Rout, Sun, Tam, von Mering, Wallner, Wiederstein, World Health Organization, Yang, Yeh, Zhexin   +45 more
core   +1 more source

Safety of a fixed-dose combination of artesunate and amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in real-life conditions of use in Côte d’Ivoire [PDF]

, 2017
Additional file 2.
Abouo Franklin Nguessan, Emmanuel Bissagnéné, Jean Claude Yavo, Koffi Moïse San, Mea Antoine Tanoh, N’cho Bertin Tchiekoi, Serge-Brice Assi, Stephan Duparc, Valérie Lameyre, Yapo Thomas Aba   +9 more
core   +3 more sources

Distribution of the cytochrome P450 CYP2C8*2 allele in Brazzaville, Republic of Congo

International Journal of Infectious Diseases, 2019
Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. Individuals carrying the CYP2C8*
Simon Marie Peko, Francine Ntoumi, Christevy Vouvoungui, David Nderu, Simon Charles Kobawila, Thirumalaisamy P. Velavan, Félix Koukouikila-Koussounda   +6 more
doaj   +1 more source

Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component [PDF]

, 1996
Shaun R. Hawley, P. G. Bray, Paul M. O’Neill, Dean J. Naisbitt, B K Park, Stephen A. Ward   +5 more
openalex   +1 more source