Results 41 to 50 of about 14,011 (208)

Low-Cost and Portable Biosensor Based on Monitoring Impedance Changes in Aptamer-Functionalized Nanoporous Anodized Aluminum Oxide Membrane

Micromachines
We report a low-cost, portable biosensor composed of an aptamer-functionalized nanoporous anodic aluminum oxide (NAAO) membrane and a commercial microcontroller chip-based impedance reader suitable for electrochemical impedance spectroscopy (EIS)-based ...
Nianyu Jiang, Pranav Shrotriya
doaj   +1 more source

Synthesis and Evaluation of Some New Isoquine Analogues for Antimalarial Activity

E-Journal of Chemistry, 2009
Amodiaquine is a 4-aminoquinoline antimalarial that can cause adverse side effects including hepatic and haematological toxicity. The drug toxicity involves the formation of an electrophilic metabolite, amodiaquine quinoneimine (AQQI), which binds to ...
Chandra Nath Saha, Sanjib Bhattacharya, Dipak Chetia   +2 more
doaj   +1 more source

Time to Act; Let Us Unite to Eliminate Malaria Among Pregnant Women in War Zone From Eastern Democratic Republic of the Congo: A Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Malaria remains a major public health challenge in sub‐Saharan Africa, with the Democratic Republic of the Congo (DR Congo) contributing substantially to the global burden. DR Congo accounts for 12% of global malaria cases. This study aims to assess the intersectionality of epidemiological, immunological, and conflict‐related ...
Aymar Akilimali, Laiba Mehmood, Paradzai Innocent Njazi, Babar Ali, Saad Maqbool, Muhammad Younas, Martin Sagide, Syeda Vilay Zehra Rizvi, Rabbia Munsab, Syeda Umme Abiha Rizvi, Sabika Fatima, Amidu Alhassan, Calvin R. Wei, Amos Kipkorir Langat   +13 more
wiley   +1 more source

Eficacia de la combinación amodiaquina más sulfadoxinapirimetamina y de la cloroquina para el tratamiento del paludismo en Córdoba, Colombia, 2006

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. La disminución de la eficacia de los medicamentos antipalúdicos en el mundo y en Colombia, dificulta el control de la enfermedad. Objetivo.
Manuel Alberto Pérez, Liliana Jazmín Cortés, Ángela Patricia Guerra, Angélica Knudson, Carlos Usta, Rubén Santiago Nicholls   +5 more
doaj   +1 more source

Synthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparum. [PDF]

PLoS ONE, 2015
The efficacy of chloroquine, once the drug of choice in the fight against Plasmodium falciparum, is now severely limited due to widespread resistance.
Chandima S K Rajapakse, Maryna Lisai, Christiane Deregnaucourt, Véronique Sinou, Christine Latour, Dipankar Roy, Joseph Schrével, Roberto A Sánchez-Delgado   +7 more
doaj   +1 more source

Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania. [PDF]

, 2006
Artemisinin-based combination therapies (ACTs) are recommended for use against uncomplicated malaria in areas of multi-drug resistant malaria, such as sub-Saharan Africa.
Kefas Mugittu, Blaise Genton, Hassan Mshinda, Hans Peter Beck, The East African Network for Monitoring Antimalarial Treatment (EANMAT), AO Talisuna, K Mugittu, PE Duffy, U Eckstein-Ludwig, AC Uhlemann, R Jambou, SP Kachur, C Falade, RN Price, MT Duraisingh, A Afonso   +15 more
core   +2 more sources

Eficacia terapéutica y eventos adversos de tratamientos para malaria vivax y malaria falciparum en gestantes en las regiones de Urabá y Alto San Jorge, Colombia, 2008-2011 Therapeutic efficacy and adverse events of treatments for vivax and falciparum malaria in pregnant women in the regions of Uraba and Alto San Jorge, Colombia, 2008-2011

Revista Colombiana de Obstetricia y Ginecología, 2013
Objetivo: evaluar, con el protocolo de la Organización Mundial de la Salud (OMS) de 1998, la respuesta terapéutica antimalárica (RTA) y los eventos adversos (EA) en cuatro esquemas de tratamiento antiplasmodial en gestantes colombianas, con diagnóstico ...
Jaime Carmona-Fonseca, Olga María Agudelo-García, Eliana Arango-Flórez   +2 more
doaj  

Polimorfismos del gen pfmdr1 en muestras clínicas de Plasmodium falciparum y su relación con la respuesta terapéutica a antipalúdicos y paludismo grave en Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. El gen pfmdr1 de Plasmodium falciparum se describió como un gen de resistencia a diversos antipalúdicos. Sin embargo, no se han estudiado el papel de su polimorfismo en la respuesta terapéutica al tratamiento con antipalúdicos en Colombia ...
Paula Montoya, Alberto Tobón, Silvia Blair, Jaime Carmona, Amanda Maestre   +4 more
doaj   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Gametocytaemia in senegalese children with uncomplicated Falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine

Parasite, 2001
Plasmodium falciparum gametocytaemia was studied in 266 Senegalese children (median 4 years, range 0.5-16) with uncomplicated malaria treated with chloroquine (CQ), amodiaquine (AQ) or sulfadoxine+pyrimethamine (SP).
Sokhina C.S, Trape J.-F, Robert V.
doaj   +1 more source