Results 1 to 10 of about 114,473 (186)
Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases [PDF]
Frontiers in Plant Science, 2014 The SNF1-related protein kinases 1 (SnRK1s) are the plant orthologs of the budding yeast SNF1 (Sucrose Non-Fermenting 1) and mammalian AMPK (AMP-activated protein kinase).
Pierre eCrozet +8 more
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The Role of AMPKα in the Mechanism of Development and Treatment of Heart Failure [PDF]
Reviews in Cardiovascular MedicineThe AMP-activated protein kinase (AMPK) alpha (AMPKα) subunit is the catalytic subunit in the AMPK complex and includes both α1 and α2 isoforms. Phosphorylation of upstream kinases at the Thr172 site in the α-subunit is critical for AMPK activation.
Yue Feng +3 more
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AMP-Activated Protein Kinase Signalling [PDF]
International Journal of Molecular Sciences, 2019 AMP-activated protein kinase (AMPK) regulates energy homeostasis in eukaryotic cells and organisms [...]
Dietbert Neumann, Benoit Viollet
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AMP-Activated Protein Kinase [PDF]
Circulation: Arrhythmia and Electrophysiology, 2012 AMP-activated protein kinase (AMPK), a serine/threonine kinase, is a highly conserved homeostatic regulatory enzyme with a plethora of important roles in energy storage and use. ATP is the primary cellular energy source; in situations of metabolic deficiency, its breakdown product AMP accumulates.
Dieter Böning +46 more
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Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): This research was designed to determine the role of irisin in lipopolysaccharide (LPS)-induced endometritis in female mice. Materials and Methods: Animals were randomly assigned into sham, sham + irisin, LPS, LPS + irisin (0.1, 1, 10 μg/kg),
Xi Jiang +11 more
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Is 5´-AMP-Activated Protein Kinase Both Jekyll and Hyde in Bladder Cancer? [PDF]
International Neurourology Journal, 2015 The 5´-AMP-activated protein kinase (AMPK) is a key regulator of cellular metabolism and energy homeostasis in mammalian tissues. Metabolic adaptation is a critical step in ensuring cell survival during metabolic stress.
Wun-Jae Kim
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AMP-Activated Protein Kinase and Autophagy [PDF]
Autophagy, 2007 Autophagy is inhibited by TOR-dependent signaling. Interruption of signalling by rapamycin is known to stimulate autophagy, both in mammalian cells and in yeast. However, inactivation of TOR by AMPK has yielded controversial results in the literature with regard to its effect on autophagy: activation of autophagy in yeast but inhibition in hepatocytes.
Meijer, Alfred, Codogno, Patrice
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Journal of Ginseng Research, 2020 Background: Ginsenoside compound-Mc1 (Mc1) is a member of the deglycosylated ginsenosides obtained from ginseng extract. Although several ginsenosides have a cardioprotective effect, this has not been demonstrated in ginsenoside Mc1.
So-hyeon Hong +8 more
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Vav3, a GEF for RhoA, Plays a Critical Role under High Glucose Conditions [PDF]
Endocrinology and Metabolism, 2014 BackgroundThe role of small GTPase molecules is poorly understood under high glucose conditions.MethodsWe analyzed the expression pattern of Vav3 in skeletal muscle C2C12 cells under high glucose culture condition with reverse transcription-polymerase ...
Jie Sha +11 more
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Controls of Nuclear Factor-Kappa B Signaling Activity by 5’-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer Cells [PDF]
International Neurourology Journal, 2016 Generally, both lipopolysaccharide (LPS)- and hypoxia-induced nuclear factor kappa B (NF-κB) effects are alleviated through differential posttranslational modification of NF-κB phosphorylation after pretreatment with 5´-AMP-activated protein kinase (AMPK)
Bo-Hwa Choi +4 more
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