Results 271 to 280 of about 114,592 (304)
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The regulation of AMP-activated protein kinase by upstream kinases
International Journal of Obesity, 2008AMP-activated protein kinase (AMPK) is the downstream component of a protein kinase cascade that plays a major role in maintaining energy homoeostasis. Within individual cells, AMPK is activated by a rise in the AMP/ATP ratio that occurs following a fall in ATP levels.
D, Carling, M J, Sanders, A, Woods
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AMP-activated protein kinase: balancing the scales
Biochimie, 2005AMP-activated protein kinase (AMPK) is the central component of a protein kinase cascade that plays a key role in the regulation of energy control. AMPK is activated in response to an increase in the ratio of AMP:ATP within the cell. Activation requires phosphorylation of threonine 172 within the catalytic subunit of AMPK by an upstream kinase.
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AMP‐activated protein kinase and muscle glucose uptake
Acta Physiologica Scandinavica, 2003AbstractThe AMP‐activated protein kinase (AMPK) is an enzyme that is activated in situations where there are changes in the cellular energy status such as muscle contraction and hypoxia. AMPK can also be pharmacologically activated by the compound 5‐aminoimidazole‐4‐carboxamide ribonucleoside (AICAR) and the antidiabetic agent metformin.
N, Musi, L J, Goodyear
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Intracellular signaling of the AMP-activated protein kinase
2019AMP-activated protein kinase (AMPK) is an essential cellular energy sensor that senses the cellular energy status and maintains cellular energy balance. The AMPK coordinates cellular and whole-body energy homeostasis through stimulating catabolic ATP-producing and suppressing anabolic ATP-consuming intracellular signaling pathways.
Miribane, Dërmaku-Sopjani +1 more
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AMP-Activated Protein Kinase in Liver
2009The AMP-activated protein kinase (AMPK) has become an inescapable topic in metabolic disorders. AMPK is a highly conserved eukaryotic protein serine/threonine kinase, which is involved in energy homeostasis both at the cellular and whole-body levels [1–3].
Louis Hue, Laurent Bultot, Mark H. Rider
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Mitogen‐activated protein kinase cascades in plant signaling
Journal of Integrative Plant Biology, 2022Mengmeng Zhang, Shuqun Zhang
exaly
Peptide substrates for AMP-activated protein kinase
Biochemical Society Transactions, 1995C M, Toomey +4 more
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AMP-activated protein kinase: the current landscape for drug development
Nature Reviews Drug Discovery, 2019Gregory R Steinberg, David Carling
exaly