Oral Supplementation With a Bovine Thymus Extract Reduces Neuronal Excitability in Aging Mice
Oral supplementation of aging mice with a nuclear fraction extract of bovine thymus (TNF) leads to significant increases in GAD65, GAD67, and β2/β3 subunits of the GABAA receptor, more so with high dose (HD) TNF treatment compared to low dose (LD) and control condition.
Abdeslem El‐Idrissi +2 more
wiley +1 more source
Glutamate-Dependent Dynamic DNA Methylation Regulates Excitatory Amino Acid Transporters in Bergmann Glia Cells: Role of AMPA Receptors. [PDF]
Oyetayo BO +11 more
europepmc +1 more source
Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice
Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy +9 more
wiley +1 more source
Associations of glyphosate and aminomethylphosphonic acid (AMPA) concentrations with birth outcomes in pregnant women from the Midwestern U.S. [PDF]
Morris KA +8 more
europepmc +1 more source
α7 Nicotinic Acetylcholine Receptors Occur at Postsynaptic Densities of AMPA Receptor-Positive and -Negative Excitatory Synapses in Rat Sensory Cortex [PDF]
Robert B. Levy, Chiye Aoki
openalex +1 more source
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
wiley +1 more source
Glial Cell AMPA Receptors in Nervous System Health, Injury and Disease [PDF]
María Ceprián, Daniel Fulton
openalex +1 more source
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando +7 more
wiley +1 more source
Neurological diversity and generalizability: building on AMPA receptor imaging advances in long COVID. [PDF]
Rudroff T.
europepmc +1 more source

