Results 181 to 190 of about 70,772 (270)

Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3461-3465, June 2026.
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck   +1 more
wiley   +1 more source

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley   +1 more source

Brainstem Astrocytes Regulate Estrus‐Dependent Oscillations in Food Intake

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
DVC astrocytes regulate food intake and caloric balance via modulation of NMDA receptor‐mediated glutamatergic signaling to brainstem DMV motoneurons. In female rats, GFAP‐IR intensity and astrocyte morphological complexity increased during periods of high estrogen levels when food intake was decreased, and chemogenetic manipulation of DVC astrocytes ...
K. Selin Ozkaya   +4 more
wiley   +1 more source

Functional Ca<sup>2+</sup>-permeable AMPA receptors in hippocampal astrocytes mediate calcium signaling in vitro. [PDF]

open access: yesSci Rep
Picañol J   +8 more
europepmc   +1 more source

Lateral hypothalamic melanin concentrating hormone‐expressing neurons both promote and are required for cue‐potentiated feeding

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Food‐related stimuli can promote feeding behaviors independent of metabolic need. Cue‐potentiated feeding (CPF) studies in rodents offer the potential to reveal the psychobiological mechanisms underlying learned overeating behaviors. We examined whether lateral hypothalamic area (LHA) cells expressing the feeding signal Melanin Concentrating ...
Lauren M. Raycraft   +4 more
wiley   +1 more source

Synergistic antitumor effect of temozolomide and perampanel in pediatric glioma: a case report and in vitro validation using patient-derived glioma sphere cells. [PDF]

open access: yesActa Neuropathol Commun
Omachi T   +11 more
europepmc   +1 more source

The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae

open access: yesTraffic, Volume 27, Issue 2, June 2026.
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhibits vacuolar fragmentation, enlarged lipid droplets, and metabolic alterations. Ruiz Salas, J. L. (2026) https://BioRender.com/b65g523. ABSTRACT Erv14 is a
Paul Rosas‐Santiago   +12 more
wiley   +1 more source

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