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The AMPA receptors of auditory neurons
Hearing Research, 2000The ionotropic glutamate receptor (GluR) subtype known as the AMPA receptor, which mediates rapid excitatory synaptic transmission in many regions of the nervous system, is composed of four different protein subunits, termed GluRs 1-4. The functional properties of each AMPA receptor are determined by the relative levels of GluRs 1-4 and by post ...
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In Search of Novel AMPA Potentiators
Recent Patents on CNS Drug Discovery, 2006Glutamate is the major excitatory neurotransmitter in the brain. Amongst ionotropic receptors responding to glutamate, the AMPA subtype has been considered as essential for the fast excitatory neurotransmission in the central nervous system and the expression and maintenance of long-term potentiation.
Pierre Francotte+5 more
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AMPA Receptor Trafficking and GluR1
Science, 2005In their Research Article “Postsynaptic receptor trafficking underlying a form of associative learning” (1 Apr., p. 83), S. Rumpel et al. draw the important conclusions that “encoding of memories in the lateral amygdala is mediated by AMPA receptor trafficking” and that “synaptic incorporation of AMPARs is necessary for learning.” The key experiment ...
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AMPA receptor trafficking and synaptic plasticity.
Annual Review of Neuroscience, 2002R. Malinow, R. Malenka
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Visualization of AMPA receptors in living human brain with positron emission tomography
Nature Network Boston, 2020Tomoyuki Miyazaki+36 more
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Synaptic AMPA receptor composition in development, plasticity and disease
Nature Reviews Neuroscience, 2016J. Henley, K. Wilkinson
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Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking.
Annual Review of Physiology, 2016B. Herring, R. Nicoll
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A Photochromic Agonist of AMPA Receptors
Angewandte Chemie International Edition, 2012Stawski, P.; Sumser, M.; Trauner, D.
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