Results 141 to 150 of about 14,818 (181)
Some of the next articles are maybe not open access.
Diagnostic Microbiology and Infectious Disease, 2021
There is minimal data on the optimal treatment of lower inoculum infections such as urinary tract infections (UTIs) caused by SPICE organisms which encode the betalactamase enzyme, AmpC. This single-center, retrospective review of adult hospitalized patients with UTIs caused by a SPICE organism compared outcomes amongst patients treated with drugs ...
Julia, Sapozhnikov +3 more
openaire +2 more sources
There is minimal data on the optimal treatment of lower inoculum infections such as urinary tract infections (UTIs) caused by SPICE organisms which encode the betalactamase enzyme, AmpC. This single-center, retrospective review of adult hospitalized patients with UTIs caused by a SPICE organism compared outcomes amongst patients treated with drugs ...
Julia, Sapozhnikov +3 more
openaire +2 more sources
Clinical Microbiology Reviews, 2009 SUMMARYAmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae and a few other organisms, where they mediate resistance to cephalothin, cefazolin, cefoxitin, most penicillins, and β-lactamase inhibitor-β-lactam combinations.
exaly +2 more sources
Plasmid-borne AmpC β-lactamases
Canadian Journal of Microbiology, 2002Historically, it was thought that ampC genes encoding class C β-lactamases were located solely on the chromosome but, within the last 12 years, an increasing number of ampC genes have been found on plasmids. These have mostly been acquired by ampC-deficient pathogenic bacteria, which consequently are supplied with new and additional resistance ...
Jan, Walther-Rasmussen, Niels, Høiby
openaire +2 more sources
Nanomolar Inhibitors of AmpC β-Lactamase
Journal of the American Chemical Society, 2002beta-lactamases are the most widespread resistance mechanism to beta-lactam antibiotics, such as the penicillins and the cephalosporins. In an effort to combat these enzymes, a combination of stereoselective organic synthesis, enzymology, microbiology, and X-ray crystallography was used to design and evaluate new carboxyphenyl-glycylboronic acid ...
MORANDI, federica +6 more
openaire +3 more sources
Journal of Antimicrobial Chemotherapy, 2018
AmpC β-lactamases are encoded on the chromosomes of certain Enterobacterales and lead to clinical resistance to various β-lactams in case of high-level expression. In WT bacteria with inducible AmpC, the expression is low, but selection of stably ampC-derepressed mutants may occur during β-lactam therapy.
Rebekka, Kohlmann +2 more
openaire +2 more sources
AmpC β-lactamases are encoded on the chromosomes of certain Enterobacterales and lead to clinical resistance to various β-lactams in case of high-level expression. In WT bacteria with inducible AmpC, the expression is low, but selection of stably ampC-derepressed mutants may occur during β-lactam therapy.
Rebekka, Kohlmann +2 more
openaire +2 more sources
Detection of AmpC beta-lactamases using sodium salicylate
Journal of Microbiological Methods, 2012AmpC β-lactamases are enzymes that hydrolyze all β-lactam antibiotics except cefipime and imipenem. Currently, there is no standard phenotypic method for detection of such enzymes. This study aims to report the use of sodium salicylate for AmpC β-lactamases detection and to compare its sensitivity and specificity to other commonly known inhibitors.
Mona T, Kashif +2 more
openaire +2 more sources
Signalling proteins in enterobacterial AmpC β‐lactamase regulation
Molecular Microbiology, 1989SummaryThe cloned Citrobacter freundii ampC β‐lactamase is inducible in the presence of its regulatory gene ampR in Escherichia coli (Lindberg et al., 1985). The basal level of expression and inducibility are affected by two E. coli proteins encoded by the closely linked ampD and ampE genes.
S, Lindquist +3 more
openaire +2 more sources