Results 41 to 50 of about 10,352,886 (166)

Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis

open access: yesELECTROPHORESIS, EarlyView.
Most recent advances for the enhancement of sensitivity in capillary electrophoresis, including off‐line and in‐capillary preconcentration techniques and their combinations, and the use of alternative detection systems to UV–Vis spectrophotometric absorption.
María Castro‐Puyana   +2 more
wiley   +1 more source

Occupational conditions and the risk of the use of amphetamines by truck drivers

open access: yesRevista de Saúde Pública, 2015
OBJECTIVE To test whether the occupational conditions of professional truck drivers are associated with amphetamine use after demographic characteristics and ones regarding mental health and drug use are controlled for.METHODS Cross-sectional study, with
Lúcio Garcia de Oliveira   +6 more
doaj   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado   +9 more
wiley   +1 more source

Modulatory Effects of Methadone on Brain Network Instability in Methamphetamine Use; A Cross-sectional Study

open access: yesArchives of Academic Emergency Medicine
Introduction: While methadone maintenance therapy (MMT) is well established in opioid use disorder, its potential modulatory effects on brain network dynamics in methamphetamine use disorder (MUD) remain unclear.
javad sheikhi Koohsar   +9 more
doaj   +1 more source

Prediction of psychiatric comorbidity on premature death in a cohort of patients with substance use disorders: a 42-year follow-up

open access: yesBMC Psychiatry, 2019
Background We need to better understand how the use of different substances and psychiatric comorbidity influence premature death generally and cause-specific death by overdose, intoxication and somatic disorders in people with substance use disorders ...
Mats Fridell   +5 more
doaj   +1 more source

Supplement_material – Supplemental material for Amphetamine–Dextroamphetamine and Pregnancy: Neonatal Outcomes After Prenatal Prescription Mixed Amphetamine Exposure

open access: yes, 2020
Supplemental material, Supplement_material for Amphetamine–Dextroamphetamine and Pregnancy: Neonatal Outcomes After Prenatal Prescription Mixed Amphetamine Exposure by Sherrill J. Rose, Matthew A. Hathcock, Wendy M.
Kristi Borowski (8306292)   +4 more
core   +1 more source

Transdiagnostic and symptom‐domain associations between mental illnesses and future self‐connectedness versus future self‐valence

open access: yesJCPP Advances, EarlyView.
Abstract Background Future time perspective dimensions have been linked to various mental illnesses. Given the tendency for mental illnesses to co‐occur, it is necessary to disentangle associations between future‐oriented constructs and shared versus symptom‐domain‐specific psychopathology.
Yi Yang   +6 more
wiley   +1 more source

The Histaminergic Tuberomamillary Nucleus Is Involved in Appetite for Sex, Water and Amphetamine. [PDF]

open access: yesPLoS ONE, 2016
The histaminergic system is one component of the ascending arousal system which is involved in wakefulness, neuroendocrine control, cognition, psychiatric disorders and motivation.
Marco Contreras   +6 more
doaj   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu   +15 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

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