Rationale: Lisdexamfetamine is a prodrug of D-amphetamine used for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a prolonged pharmacokinetic profile compared with oral D-amphetamine, possibly ...
Patrick C. Dolder +5 more
doaj +1 more source
Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine. [PDF]
Amphetamine, a highly addictive drug with therapeutic efficacy, exerts paradoxical effects on the fundamental communication modes employed by dopamine neurons in modulating behavior.
Dan P Covey +2 more
doaj +1 more source
The spectroscopic detection of drugs of abuse in fingerprints after development with powders and recovery with adhesive lifters [PDF]
The application of powders to fingerprints has long been established as an effective and reliable method for developing latent fingerprints. Fingerprints developed in situ at a crime scene routinely undergo lifting with specialist tapes and are then ...
Went, Michael J., West, M.J.
core +1 more source
Risk Factors for Opioids and Stimulants Poisoning among Patients Admitted to Khorshid Hospital in Isfahan [PDF]
Background: Poisoning by opium and stimulants brings many patients to the poison emergency departments every year. This study planned to determine the risk factors for Opioid and Stimulant poisoning among patients admitted to the Khorshid Hospital ...
Gholamali Dorooshi +5 more
doaj +1 more source
Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors [PDF]
Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Bermeo, C. +6 more
core +1 more source
Prevalence of Substance Abuse among Teenagers in Damietta Governorate [PDF]
Background: Substance misuse among teenagers has increased dramatically in recent years, and drug abuse amongst younger people has also steadily increased, with more youngsters beginning to use substances at a young age.The Aim of the work: The purpose ...
Mohamed Nasr +4 more
doaj +1 more source
In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. [PDF]
INTRODUCTION: We examined whether [(18)F]LBT-999 ((E)-N-(4-fluorobut-2-enyl)2β-carbomethoxy-3β-(4'-tolyl)nortropane) is an efficient positron emission tomography (PET) tracer for the quantification of the dopamine transporter (DAT) in the healthy rat ...
Chalon, Sylvie +7 more
core +1 more source
Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]
Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core +1 more source
Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinical symptoms.
Xu Tong, Sagvolden Terje
doaj +1 more source
Adolescent D-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood [PDF]
RATIONALE: Stimulant medications for attention-deficit/hyperactivity disorder (ADHD) in adolescents remain controversial with respect to later development of cocaine abuse.
Dwoskin, Linda P. +3 more
core +1 more source

