Results 31 to 40 of about 122,177 (317)

In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. [PDF]

, 2013
INTRODUCTION: We examined whether [(18)F]LBT-999 ((E)-N-(4-fluorobut-2-enyl)2β-carbomethoxy-3β-(4'-tolyl)nortropane) is an efficient positron emission tomography (PET) tracer for the quantification of the dopamine transporter (DAT) in the healthy rat ...
Chalon, Sylvie, Deloye, Jean-Bernard, Galineau, Laurant, Garreau, Lucette, Guilloteau, Denis, Sérrière, Sophie, Tauber, Clovis, Vercouillie, Johnny   +7 more
core   +1 more source

Amphetamine, but not methylphenidate, increases ethanol intake in adolescent male, but not in female, rats [PDF]

, 2018
Introduction: There has been an increasing interest in analyzing the interactions between stimulants and ethanol during childhood and adolescence. Stimulants are used to treat attention-deficit hyperactivity disorder (ADHD) in these developmental stages,
Acevedo, Adriani, Aleksandrov, Andersen, Atianjoh, Berardo, Brandon, Brunelle, Burke, Camarini, Chong, Crawford, Crowley, Cryan, Dalsgaard, Diaz Heijtz, Doremus-Fitzwater, Duke, Fahlke, Feltmann, Fernandez, Frey, Frolov, Gaytan, Gaytan, Gaytan, Gaytan, Gill, Gowin, Heinz, Izenwasser, Jones, Justo, Kameda, Karanikas, Karim, Kozanian, Krasnova, Kuczenski, Kuczenski, Lambert, Mandt, Mannuzza, McClintick, McCullough, McDougall, McDougall, Naimi, National-Research-Council, Pascual, Pilatti, Pilatti, Pilatti, Pinsky, Ponce, Quinn, Quinn, Renard, Ruiz, Salisbury, Schenk, Schuckit, Schuckit, Soeters, Spear, Spear, Sripada, Stewart, Strakowski, Tirelli, Vendruscolo, Venkataraman, Venniro, Wagner, Wetzell, Wille-Bille, Winer, Wolgin   +77 more
core   +1 more source

Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD

Frontiers in Behavioral Neuroscience, 2015
Psychostimulants show therapeutic efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD). It is generally assumed that they ameliorate ADHD symptoms via interfering with monoaminergic signaling.
Yi-Chun eYen, Nils C. Gassen, Andreas eZellner, Theo eRein, Rainer eLandgraf, Carsten T. Wotjak, Elmira eAnderzhanova   +6 more
doaj   +1 more source

Analysis of amphetamines illegally produced in Serbia [PDF]

Journal of the Serbian Chemical Society, 2008
Forensic practice in the Republic of Serbia faced the illegal production of amphetamine for the first time in 2003. This paper presents the results of the chemical characterization of 32 batches of amphetamine samples from three separate cases, for the ...
Nevešćanin Marina, Banović-Stević Sonja, Petrović Slobodan, Vajs Vlatka   +3 more
doaj   +1 more source

Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]

, 2016
Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H, Mattingly, Gregory W   +1 more
core   +2 more sources

Circadian melatonin profile in opium and amphetamine dependent patients: A preliminary study

Neurobiology of Sleep and Circadian Rhythms, 2019
Aim: The aim of this study was to investigate the relationship between opium and amphetamine dependency with the serum melatonin levels in the presence of circadian rhythm sleep disorders (CRSD).
Habibolah Khazaie, MD, Hamid Reza Ahmadi, MD, Amir Kiani, PhD, Mohammad Rasoul Ghadami, MD   +3 more
doaj   +1 more source

Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]

, 2018
RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Fatal intoxication after oral ingestion of amphetamine: Two case reports

Forensic Science International: Synergy
Amphetamine is a stimulant that is abused worldwide and e.g. leads to hyperthermia [Brinkman et al., 2014], dizziness, insomnia, stomachaches and suppression of appetite [Callaway et al., 1994].
Evelyn Pawlik, Felix Mayer, Oliver Temme
doaj   +1 more source

Analysis of amphetamine and methamphetamine contents in seized tablets from Jazan, Saudi Arabia by liquid chromatography-mass spectroscopy (LC-MS/MS) and chemometric techniques

Saudi Pharmaceutical Journal, 2020
A number of illegal amphetamine tablets were seized from three different cities of Jazan province of southern Saudi Arabia and were analyzed for amphetamine and methamphetamine contents using LC-MS/MS technique. Analyses were performed using a previously
Hassan A. Alhazmi, Waquar Ahsan, Mohammed Al Bratty, Sadique A. Javed, Karam A. El-Sharkawy, Asaad Khalid, Hussain M. Alsalem, Ahmed M. Hakami, Mohammad A. Attafi, Magbool E. Oraiby   +9 more
doaj   +1 more source