Results 51 to 60 of about 5,285 (203)

Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer

open access: yeseLife, 2020
Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
doaj   +1 more source

Metamorphosis and lncRNAs: A Close Relationship

open access: yesgenesis, Volume 64, Issue 2, April 2026.
ABSTRACT The classical definition of metamorphosis is a post‐embryonic transformation, such as from a tadpole to a froglet. However, recent studies suggest this process occurs to some degree in all vertebrates, as the underlying endocrine and molecular pathways are highly conserved. With the advent of high‐throughput sequencing, transcriptomic data for
H. Herrera‐Orozco   +1 more
wiley   +1 more source

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang   +13 more
wiley   +1 more source

Amylase in Amphioxus [PDF]

open access: yesNature, 1939
SPECIMENS of Amphioxus caribbaeum collected while working at the Tortugas Laboratory of the Carnegie Institution of Washington were examined with respect to the amylase present in the gut. Determinations were carried out by the micro-method of Linderstrom-Lang and Holter as modified by Holter and Doyle1.
openaire   +1 more source

Exploring developmental, functional, and evolutionary aspects of amphioxus sensory cells

open access: yesInternational Journal of Biological Sciences, 2006
Amphioxus has neither elaborated brains nor definitive sensory organs, so that the two may have evolved in a mutually affecting manner and given rise to the forms seen in extant vertebrates.
Gouki Satoh
doaj  

Toward Next‐Generation Teratology: Understanding Developmental Vulnerability Through Evolutionary and Comparative Genomics

open access: yesCongenital Anomalies, Volume 66, Issue 1, January/December 2026.
ABSTRACT Teratology, the study of congenital anomalies, has developed from a descriptive discipline into a mechanistic science focused on the proximate causes of developmental defects, meaning how such anomalies arise during development. However, a comprehensive understanding requires not only this mechanistic insight but also an evolutionary ...
Tetsuo Kon
wiley   +1 more source

Zur Physiologie des Centralnervensystems von Amphioxus

open access: yes, 1892
ZUR PHYSIOLOGIE DES CENTRALNERVENSYSTEMS VON AMPHIOXUS Zur Physiologie des Centralnervensystems von Amphioxus (52) (-
Danilewsky, Basile
core   +2 more sources

Comparative Genomics of Sex‐Determination‐Related Genes Reveals Shared Evolutionary Patterns Between Bivalves and Mammals, but Not Fruit Flies

open access: yesMolecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT The molecular basis of sex determination (SD), while being extensively studied in model organisms, remains poorly understood in many animal groups. Bivalves, a diverse class of molluscs with a variety of reproductive modes, represent an ideal yet challenging clade for investigating SD and the evolution of sexual systems.
Filippo Nicolini   +4 more
wiley   +1 more source

Gene duplications in the prototypical cephalochordate amphioxus.

open access: yes, 2002
The new discipline of Evolutionary Developmental Biology (Evo-Devo) is facing the fascinating paradox of explaining morphological evolution using conserved pieces or genes to build divergent animals.
Cebrián, C.   +3 more
core   +1 more source

The relationship between microbial community succession, decay, and anatomical character loss in non‐biomineralized animals

open access: yesPalaeontology, Volume 68, Issue 5, September/October 2025.
Abstract A fundamental assumption of hypothesis‐driven decay experiments is that, during decay, the loss of anatomy follows a sequence broadly controlled by the intrinsic compositional properties of tissues. Recent work investigating the succession of postmortem endogenous microbial communities (thanatomicrobiome) challenges this assumption in that the
Thomas Clements   +8 more
wiley   +1 more source

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