Results 121 to 130 of about 374,595 (258)

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Amphotericin B and Filipin Effects on L and HeLa Cells: Dose Response [PDF]

open access: green, 1977
J Kotler-Brajtburg   +3 more
openalex   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Amphotericin B resistance in Leishmania amazonensis: In vitro and in vivo characterization of a Brazilian clinical isolate.

open access: yesPLoS Neglected Tropical Diseases
In Brazil, Leishmania amazonensis is the etiological agent of cutaneous and diffuse cutaneous leishmaniasis. The state of Maranhão in the Northeast of Brazil is prevalent for these clinical forms of the disease and also has high rates of HIV infection ...
Bianca A Ferreira   +7 more
doaj   +1 more source

A mitochondria‐targeted aggregation‐induced emission photosensitizer for eradication Candida biofilms and treating oral ulcer

open access: yesSmart Molecules, EarlyView.
A mitochondria‐targeted AIE photosensitizer, LIQ‐TPA‐TZ, was developed to fight against Candida infection. It can efficiently produce reactive oxygen species to kill Candida guilliermondii and eradicate biofilms. It not only disrupted the respiratory chain and affected the metabolism and energy supply but also reduced the fungi adhesion and filament ...
Kun‐Mei Liu   +5 more
wiley   +1 more source

The ring of perfect $p$-permutation bimodules for blocks with cyclic defect groups [PDF]

open access: yesarXiv
Let $B$ be a block algebra of a group algebra $FG$ of a finite group $G$ over a field $F$ of characteristic $p>0$. This paper studies ring theoretic properties of the representation ring $T^\Delta(B,B)$ of perfect $p$-permutation $(B,B)$-bimodules and properties of the $k$-algebra $k\otimes_\mathbb{Z} T^\Delta(B,B)$, for a field $k$.
arxiv  

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

open access: yesSmall Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton   +3 more
wiley   +1 more source

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