Results 121 to 130 of about 95,889 (290)

Amphotericin B plus 1,3-BIS (2-chloroethyl)-1-nitrosourea (BCNU-NSC NO. 409962) in advanced cancer.Phase I and preliminary phase II results [PDF]

, 1976
Cary A. Presant, Carol Klahr, Jitka V. Olander, Diane Gatewood   +3 more
openalex   +1 more source

Crystal Structure–Activity Relationship of Some MeO Phenylacrylonitriles: Dual Antimicrobial–Cytotoxic Effects and in Silico Perspectives

ChemistryOpen, EarlyView.
Methoxy‐phenylacrylonitriles (2a–c) are synthesized and characterized by fourier‐transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and X‐ray crystallography (for 2a,b). Compound 2b shows selective cytotoxicity against MCF‐7 cells (IC50: 34 μM) and enhances activity against Gram‐positive bacteria. Molecular docking reveals strong
Leyla Babali Özen, Öner Ekici, Furkan Özen, Süleyman Berberler, Gül Özkan, Betül Yılmaz Öztürk, Pınar Oztopcu‐Vatan, Cansu Filik İşçen, Günseli Turgut Cin   +8 more
wiley   +1 more source

Cryptococcus meningitis treated with amphotericin B

, 1962
Benjamin Emanuel
openalex   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

The Clinical Experience by New Antifungal Antibiotics (Amphotericin B) on Cryptococcal Encephalomeningitis

, 1963
Minoru OKUMA, Chitose Kawakami
openalex   +2 more sources

Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis

VIEW, EarlyView.
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva, Francisco Cascalheira, Rúben Afonso, Maria Corado, Ana Martins, Cátia Caneiras, Cristina Bárbara, Miguel Cacho Teixeira, Diogo Miguel Caetano   +8 more
wiley   +1 more source

Oral amphotericin B therapy in deep-seated mycoses

, 1969
Hideo IKEMOTO, Takesi Mori, Tatsuji Kano, Yoshiyuki Uemura, R Ariwa, Toshiki Kamano, Tatsuo Nagai   +6 more
openalex   +2 more sources

Vacuolization in Cultured Cells Induced by Amphotericin B [PDF]

, 1978
Erik Lundgren, Göran Roos
openalex   +1 more source

In situ monitoring of cell adhesion kinetics using label‐free optical biosensors: Evaluating anticancer potential and selectivity of natural compounds

VIEW, EarlyView.
The limitations of conventional techniques hinder the identification of natural compounds with anticancer potential in terms of speed, throughput, sensitivity, and capability of continuous monitoring of relevant biological effects. Novel label‐free optical biosensors represent new opportunities in the discovery of drug candidates, eliminating these ...
Beatrix Péter, Tim Ausbüttel, Nicolett Kanyo, Péter Joó, Kinga Tóth, Zoltán Szittner, Inna Szekacs, Szilvia Bosze, Gábor M. Kovács, Imre Boldizsár, Robert Horvath   +10 more
wiley   +1 more source

ER Stress Ire1‐Xbp1s Pathway Maintains Youthful Epidermal Basal Layer Through the Regulation of Cell Proliferation

Aging Cell, EarlyView.
In young epidermal basal layer, the Ire1‐Xbp1s endoplasmic reticulum (ER) stress‐response pathway maintains cell proliferation by activating the cell cycle regulator Vcp, whereas the age‐dependent decline in glucose metabolism reduces Ire1‐Xbp1s activity, consequently downregulating cell proliferation.
Daniel Semmy, Kota Abe, Mizuki Honda, Hiroko Omori, Shohei Ogamino, Tobias Clausen Mercurio, Kyosuke Asakawa, Emi K. Nishimura, Shinya Oki, Yasuyuki Ohkawa, Tohru Ishitani   +10 more
wiley   +1 more source