Effects of Timing of Microbial Exposure on Microbiome Assembly and Amphibian Immune Development
Ecology and Evolution, Volume 16, Issue 8, August 2026.We used a novel amphibian gnotobiotic system to investigate how disruptions to the microbiome during critical developmental periods influence microbial assembly and the development of immunity. We found that antimicrobial treatments of embryos and subsequent introduction to microbes at different developmental stages altered microbiome assembly ...
Abigail J. Miller +5 more
wiley +1 more source
Real-World Efficacy and Safety of Liposomal Amphotericin B for Invasive Fungal Disease in Patients with Hematologic Malignancies: A Multicenter Retrospective Study. [PDF]
Drug Des Devel TherLu T +10 more
europepmc +1 more source
Macromolecular Rapid Communications, Volume 47, Issue 15, 4 August 2026.Short nanofiber fragments (SNFs) derived from electrospun PDLA/gelatin (PG) mats dynamically reassemble into conformal fibrous networks on complex substrates. This approach overcomes the geometric limitations of conventional electrospinning, enabling uniform surface coverage, enhanced wettability, and cytocompatible scaffold formation, thereby offering
Iruthayapandi Selestin Raja +7 more
wiley +1 more source
Combined anti-PD-1 and amphotericin B therapy reduces fungal burden and enhances control of murine paracoccidioidomycosis. [PDF]
Front Cell Infect MicrobiolPreite NW +7 more
europepmc +1 more source
MicrobiologyOpen, Volume 15, Issue 4, August 2026.This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino +10 more
wiley +1 more source
Clearing Candida biofilms using combined antimicrobial sophorolipids with amphotericin B and itraconazole. [PDF]
FEMS Yeast ResJayasekara LACB +5 more
europepmc +1 more source
From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez +3 more
wiley +1 more source
Isolation, structure revision and stereochemistry of trichomycins A and B, aromatic analogues of amphotericin B. [PDF]
Sci RepLaskowski T +8 more
europepmc +1 more source
Striking Bone Marrow Plasmacytosis Resulting From Visceral Leishmaniasis
American Journal of Hematology, Volume 101, Issue 8, Page 2007-2008, August 2026.
Vishakha Sovani +2 more
wiley +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source