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Antifungal Pipeline [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
In many ways, fungal diseases are forgotten or neglected. Given the significantly lower frequency compared to similar bacterial etiologies across the spectrum of infectious syndromes, it makes sense that anti-bacterial agents have seen the bulk of development in recent decades.
Todd Patrick McCarty, Todd Patrick McCarty, Peter G. Pappas   +2 more
openaire   +3 more sources

Synergistic In Vitro Interaction of Isavuconazole and Isoquercitrin against Candida glabrata

Journal of Fungi, 2022
In vitro interactions of broad-spectrum azole isavuconazole with flavonoid isoquercitrin were evaluated by a broth microdilution checkerboard technique based on the European Committee on Antimicrobial Susceptibility Testing (EUCAST) reference methodology
Petra V. Schwarz, Ilya Nikolskiy, Eric Dannaoui, Frank Sommer, Gert Bange, Patrick Schwarz   +5 more
doaj   +1 more source

Antifungal Peptides [PDF]

Journal of Fungi, 2021
Fungal infections represent an increasing public health crisis [...]
openaire   +3 more sources

Breakthrough Mucormycosis Developing on Mucorales-Active Antifungals Portrays a Poor Prognosis in Patients with Hematologic Cancer

Journal of Fungi, 2021
Although breakthrough mucormycosis (BT-MCR) is known to develop on mold-active antifungals without Mucorales activity, it can also occur while on Mucorales-active antifungals.
Dierdre B. Axell-House, Sebastian Wurster, Ying Jiang, Andreas Kyvernitakis, Russell E. Lewis, Jeffrey J. Tarrand, Issam I. Raad, Dimitrios P. Kontoyiannis   +7 more
doaj   +1 more source

Fungal Endocarditis: A Rare Cause of Left Ventricular Outflow Obstruction

Methodist DeBakey Cardiovascular Journal, 2023
A 53-year-old male presented with worsening fever, chest pain, and dyspnea during the past 2 weeks. He was hypoxic, tachycardic, and hypotensive on admission.
Elia El Hajj, Alexander Glaser, David Yancey, Allen Byl, Mehnaz Rahman   +4 more
doaj   +1 more source

Opportunistic Oesophageal Candidiasis in a Patient with COVID-19 Infection [PDF]

Journal of Clinical and Diagnostic Research, 2021
Letter to ...
Abhijit Wadekar, Sanyukta Hepat, Anamika Giri, Samarth shukla, sourya Acharya   +4 more
doaj   +1 more source

Erratum: Touil, H.F.Z. et al. Optimum Inhibition of Amphotericin-B-Resistant Candida albicans Strain in Single- and Mixed-Species Biofilms by Candida and Non-Candida Terpenoids. Biomolecules 2020, 10, 342

Biomolecules, 2020
The authors wish to make the following correction to this paper [...]
Hidaya F.Z. Touil, Kebir Boucherit, Zahia Boucherit-Otmani, Ghalia Khoder, Mohamed Madkour, Sameh S. M. Soliman   +5 more
doaj   +1 more source

Optimum Inhibition of Amphotericin-B-Resistant Candida albicans Strain in Single- and Mixed-Species Biofilms by Candida and Non-Candida Terpenoids

Biomolecules, 2020
Candida albicans is one of the most common human fungal pathogens and represents the most important cause of opportunistic mycoses worldwide. Surgical devices including catheters are easily contaminated with C.
Hidaya F. Z. Touil, Kebir Boucherit, Zahia Boucherit-Otmani, Ghalia Kohder, Mohamed Madkour, Sameh S. M. Soliman   +5 more
doaj   +1 more source

Does Protocatechuic Acid Affect the Activity of Commonly Used Antibiotics and Antifungals?

Life, 2022
The aim of this study is to evaluate the efficiency of protocatechuic acid (PCA) in enhancing the commonly used drugs used to fight against nosocomial infection. These drugs are represented by routinely used antibiotics, synthetic chemotherapeutic agents
Adrian Fifere, Ioana-Andreea Turin-Moleavin, Irina Rosca   +2 more
doaj   +1 more source

Tracking a Global Threat: a New Genotyping Method for Candida auris

mBio, 2020
Over the past decade, Candida auris has emerged as an urgent threat to public health. Initially reported from cases of ear infections in Japan and Korea, C. auris has since been detected around the world.
Christina A. Cuomo, Alexandre Alanio
doaj   +1 more source