Results 11 to 20 of about 31,747 (264)
Antifungal Combinations against Candida Species: From Bench to Bedside
Candida spp. is the major causative agent of fungal infections in hospitalized patients and the fourth most common cause of nosocomial bloodstream infection (BSI).
Simona Fioriti +5 more
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Cryptococcosis Serotypes Impact Outcome and Provide Evidence of
Cryptococcus neoformans is a human opportunistic fungal pathogen causing severe disseminated meningoencephalitis, mostly in patients with cellular immune defects. This species is divided into three serotypes: A, D, and the AD hybrid.
Marie Desnos-Ollivier +4 more
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Invasive aspergillosis (IA) has been increasingly reported in populations other than the historical hematology patients and there are new questions about the performance of microbiological tools.
Alexandre Alanio, Stéphane Bretagne
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Oxidative Imbalance in Candida tropicalis Biofilms and Its Relation With Persister Cells
BackgroundPersister cells (PCs) make up a small fraction of microbial population, can survive lethal concentrations of antimicrobial agents. In recent years, Candida tropicalis has emerged as being a frequent fungal agent of medical devices subject to ...
María A. da Silva +8 more
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‘Acridines’ as New Horizons in Antifungal Treatment
Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
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A chemometric approach for prediction of antifungal activity of some benzoxazole derivatives against Candida albicans [PDF]
The purpose of the article is to promote and facilitate prediction of antifungal activity of the investigated series of benzoxazoles against Candida albicans. The clinical importance of this investigation is to simplify design of new antifungal agents
Podunavac-Kuzmanović Sanja O. +3 more
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Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis
Candida spp. represent the third most frequent worldwide cause of infection in Intensive Care Units with a mortality rate of almost 40%. The classes of antifungals currently available include azoles, polyenes, echinocandins, pyrimidine derivatives, and ...
Marisa Conte +15 more
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Comparison of Steroid and Itraconazole for Prevention of Recurrence in Allergic Fungal Rhinosinusitis: A Randomized Controlled Trial [PDF]
Introduction: Allergic Fungal Rhinosinusitis (AFRS) is due to the continuous exposure of fungal antigens to an atopic individual. Medical treatment following the surgery is the standard protocol often practiced for the treatment of AFRS.
Moirangthem Rojita +3 more
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Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central ...
Domenico Umberto De Rose +9 more
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Computational Study of Benzimidazole Derivatives as Potential Antifungal Drugs
The infection of fungal diseases has increased in these last years due to the rise in immunodeficient patients, the resistance to current drugs, and the lack of design of new and efficient molecules against those pathogens [1]. [...]
Dorian Acevedo, Gian Pietro MIscione
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