Results 21 to 30 of about 42,196 (291)

An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]

, 2012
Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Rieger, Christina, Michael Vogeser, Ostermann, Helmut, Barbara Maier, Christina Rieger, Helmut Ostermann, Fabian Kirchhoff, Spoehrer, Ute, Vogeser, Michael, Ute Spöhrer, Maier, Barbara, Kirchhoff, Fabian   +11 more
core   +1 more source

Oxidative Imbalance in Candida tropicalis Biofilms and Its Relation With Persister Cells

Frontiers in Microbiology, 2021
BackgroundPersister cells (PCs) make up a small fraction of microbial population, can survive lethal concentrations of antimicrobial agents. In recent years, Candida tropicalis has emerged as being a frequent fungal agent of medical devices subject to ...
María A. da Silva, María A. da Silva, José L. Baronetti, José L. Baronetti, Paulina L. Páez, Paulina L. Páez, Paulina L. Páez, María G. Paraje, María G. Paraje   +8 more
doaj   +1 more source

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
core   +1 more source

‘Acridines’ as New Horizons in Antifungal Treatment

Molecules, 2020
Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
doaj   +1 more source

A chemometric approach for prediction of antifungal activity of some benzoxazole derivatives against Candida albicans [PDF]

Acta Periodica Technologica, 2012
The purpose of the article is to promote and facilitate prediction of antifungal activity of the investigated series of benzoxazoles against Candida albicans. The clinical importance of this investigation is to simplify design of new antifungal agents
Podunavac-Kuzmanović Sanja O., Jevrić Lidija J., Kovačević Strahinja Z., Kalajdžija Nataša D.   +3 more
doaj   +1 more source

Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis

Frontiers in Cellular and Infection Microbiology, 2022
Candida spp. represent the third most frequent worldwide cause of infection in Intensive Care Units with a mortality rate of almost 40%. The classes of antifungals currently available include azoles, polyenes, echinocandins, pyrimidine derivatives, and ...
Marisa Conte, Marisa Conte, Daniela Eletto, Martina Pannetta, Martina Pannetta, Anna M. Petrone, Maria C. Monti, Chiara Cassiano, Chiara Cassiano, Giorgio Giurato, Francesca Rizzo, Peter Tessarz, Peter Tessarz, Antonello Petrella, Alessandra Tosco, Amalia Porta   +15 more
doaj   +1 more source

SENSITIVITY OF Microsporum canis ISOLATED FROM DOGS TOWARDS ANTIFUNGALS [PDF]

, 2021
The dermatophytosis treatment in dogs can fail due to dermatophyte resistance to antifungals. The purpose of this study is to determine the antifungal sensitivity of dermatophyte Microsporum canis (M. canis) isolated from dogs with dermatophyte. A total
Raharjo, Slamet, Soedarmanto Indarjulianto, Yanuartono Yanuartono, Indarjulianto, Soedarmanto, Alfarisa Nururrozi, Nururrozi, Alfarisa, Gerson Yohanes I Sakan, Yanuartono, Yanuartono, Slamet Raharjo, I Sakan, Gerson Yohanes   +9 more
core   +2 more sources

Resistance to Nano-Based Antifungals Is Mediated by Biomolecule Coronas

, 2019
Fungal infections are a growing global health and agricultural threat, and current chemical antifungals may induce various side-effects. Thus, nanoparticles are investigated as potential novel antifungals.
Sven Becker (23619), Cecilia Vallet (3553226), Guo-Bin Ding (1739098), Dana Westmeier (6092036), Roland H. Stauber (166943), Eckhard Thines (220610), Shirley K. Knauer (166938), Svenja Siemer (6092033), Jens Voskuhl (1954030)   +8 more
core   +5 more sources

Comparison of Steroid and Itraconazole for Prevention of Recurrence in Allergic Fungal Rhinosinusitis: A Randomized Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Allergic Fungal Rhinosinusitis (AFRS) is due to the continuous exposure of fungal antigens to an atopic individual. Medical treatment following the surgery is the standard protocol often practiced for the treatment of AFRS.
Moirangthem Rojita, Swagatika Samal, Pradeep Pradhan, VP Venkatachalam   +3 more
doaj   +1 more source

Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies

Pharmaceuticals, 2023
Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central ...
Domenico Umberto De Rose, Iliana Bersani, Maria Paola Ronchetti, Fiammetta Piersigilli, Sara Cairoli, Andrea Dotta, Amit Desai, Laura Lynn Kovanda, Bianca Maria Goffredo, Cinzia Auriti   +9 more
doaj   +1 more source