Results 1 to 10 of about 13,816 (168)

Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report

Revista da Sociedade Brasileira de Medicina Tropical, 2019
In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate.
Benivaldo Ramos Ferreira Terceiro, Tania Salgado de Souza Torraca, Frederico Pereira Bom Braga, Ana Cristina da Costa Martins, Lucia Regina Brahim, Mauricio Naoto Saheki, Luciana de Freitas Campos Miranda, Armando de Oliveira Schubach, Cláudia Maria Valete-Rosalino   +8 more
doaj   +1 more source

Using single-dose liposomal amphotericin B for cryptococcal meningitis induction therapy: nurse pearls and practical perspectives [version 1; peer review: 2 approved]

Wellcome Open Research
Background In Uganda where the burden of HIV-associated cryptococcal meningitis is high, conventional amphotericin B deoxycholate has been standard to manage patients with cryptococcal meningitis in research settings.
Richard Kwizera, Cynthia Ahimbisibwe, Jane Frances Ndyetukira, David B. Meya, Carol Namujju   +4 more
doaj   +1 more source

Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine

Medical Mycology Case Reports, 2014
A patient with Candida spondylitis failed two weeks of fluconazole combined with caspofungin, and the infection relapsed despite six weeks of liposomal amphotericin B followed by two months of fluconazole.
Line Storm, Karen R. Lausch, Maiken C. Arendrup, Klaus L. Mortensen, Eskild Petersen   +4 more
doaj   +1 more source

Liposomal Amphotericin B

Nippon Ishinkin Gakkai Zasshi, 2005
Liposomal amphotericin B (AmBisome) is a DDS (drug delivery system) formulation of amphotericin B (AMPH-B), and has been developed in an attempt to reduce the toxicity of AMPH-B while retaining its therapeutic efficacy. AMPH-B has been the "gold standard" of antifungal therapy over the past four decades.
openaire   +3 more sources

Liposomal amphotericin B and leishmaniasis: Dose and response

Journal of Global Infectious Diseases, 2010
Liposomal amphotericin B has been used with increasing frequency to treat visceral leishmaniasis (VL). It is the treatment of choice for immunocompetent patients in the Mediterranean region and the preferred drug for HIV/VL co-infection.
Shyam Sundar, Jaya Chakravarty
doaj   +1 more source

Methods for particle size reduction of liposomal amphotericin B

Vietnam Journal of Science, Technology and Engineering, 2018
Liposomal amphotericin B were prepared by thin film hydration technique. Particle size was reduced by ultrasonic device and high pressure homogeneous device.
Tuan Quang Nguyen, Van Lam Nguyen, Thai Son Nguyen, Thi Minh Hue Pham   +3 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report

Case Reports in Infectious Diseases, 2012
We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease.
K. Grabmeier-Pfistershammer, W. Poeppl, P. M. Brunner, K. Rappersberger, A. Rieger   +4 more
doaj   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, EarlyView.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source