Results 31 to 40 of about 16,213 (203)
Liposomal Amphotericin B
Nippon Ishinkin Gakkai Zasshi, 2005 Liposomal amphotericin B (AmBisome) is a DDS (drug delivery system) formulation of amphotericin B (AMPH-B), and has been developed in an attempt to reduce the toxicity of AMPH-B while retaining its therapeutic efficacy. AMPH-B has been the "gold standard" of antifungal therapy over the past four decades.openaire +3 more sourcesLiposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India
, 2011 Reports on treatment outcomes of visceral leishmaniasis (VL)-human immunodeficiency virus (HIV) coinfection in India are lacking. To our knowledge, none have studied the efficacy of liposomal amphotericin B in VL-HIV coinfection.Pece, Manuel, Flevaud, L., Mahajan, Raman, Remartinez, D., Das, Pradeeb, Verma, Neena, Kumar, Nawin, Remartinez, Daniel, M. Pece, Ferreyra, Cecilia, Mitra, G., G. Mitra, N. Verma, Ferreyra, C., Pandey, K., Das, P., van Griensven, Johan, K. Pandey, R. Kumar, R. Mahajan, Mahajan, R., Pandey, Krishna, Kumar, Ranjeet, Mitra, Gaurab, Pece, M., P. P. Palma, Verma, N., P. Das, Kumar, Pankaj, Kumar, N., C. Ferreyra, D. Remartinez, Kumar, P., N. Kumar, Sinha, Prabhat K, Kumar, R., P. K. Sinha, van Griensven, J., Palma, P. P., Sinha, P. K., P. Kumar, Flevaud, Laurence, Palma, Pedro Pablo, J. van Griensven, L. Flevaud +44 morecore +1 more sourceEfficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.
, 2014 Cryptococcal meningoencephalitis is an urgent global health problem. Induction regimens using 14 days of amphotericin B deoxycholate (dAmB) are considered the standard of care but may not be suitable for resource-poor settings.Sharp, Andrew D, Andrew D. Sharp, Julie A. Schwartz, Gregson, Lea, Howard, Susan J, Goodwin, Joanne, Susan J. Howard, Bill Moser, John R. Perfect, Müller, W, Sharp, AD, Joanne Goodwin, Moser, Bill, Walker, Catherine, Hope, William W, Lea Gregson, Hope, WW, Perfect, John R, Joanne Livermore, Werner Müller, Schwartz, JA, William W. Hope, Felton, Timothy; id_orcid, Timothy Felton, Catherine Walker, Livermore, J, Schwartz, Julie A, Gregson, L, Goodwin, J, Harrison, Thomas S, Livermore, Joanne, Howard, SJ, Felton, T, Harrison, TS, Walker, C, Perfect, JR, Thomas S. Harrison, Müller, Werner; id_orcid, Moser, B +38 morecore +1 more sourceSingle-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis. [PDF]
, 2022 BACKGROUND: Cryptococcal meningitis is a leading cause of human immunodeficiency virus (HIV)-related death in sub-Saharan Africa. Whether a treatment regimen that includes a single high dose of liposomal amphotericin B would be efficacious is not known ...Leeme, Tshepo, Nuwagira, Edwin, Tugume, L, Hope, W, Meintjes, Graeme, Chen, Tao, Comins, Kyla, Hosseinipour, MC, Hlupeni, Admire, Chawinga, C, Singh, A, Lortholary, Olivier, Mwandumba, HC, Muzoora, Conrad, Jaffar, Shabbar, Kasibante, J., Jjunju, Samuel, Lalloo, David G, van Widenfelt, Erik, Mutata, C., Jjunju, S, Harrison, T. S., Lawrence, DS, Meya, David, Rutakingirwa, M. K., Lawrence, D. S., Jarvis, J. N., Hlupeni, A, Tugume, Lillian, Loyse, A., Harrison, Thomas S, Mutata, Constantine, Hosseinipour, M. C., Hope, William, Harrison, TS, Kagimu, Enock, Mpoza, E., Kasibante, John, Mosepele, Mosepele, Meintjes, G, Mosepele, M, Boulware, D. R., Kanyama, C., Boulware, David R, Van Widenfelt, E., Rutakingirwa, MK, Rhein, J., Youssouf, N, Comins, K, Mzinganjira, H., Mpoza, Edward, Mutata, C, Wang, D, Group, Ambition Study, Nuwagira, E., Chen, T., Hosseinipour, Mina C, Jarvis, Joseph, Lortholary, O, Boyer-Chammard, Timothée, Mwandumba, Henry, Youssouf, N., Jarvis, JN, Rhein, J, Lalloo, David, Muzoora, C., Mzinganjira, Henry, Siamisang, Keatlaretse, Lawrence, David, Rutakingirwa, Morris, Harrison, Thomas, Mosepele, M., Leeme, T, Siamisang, K., Hope, W., Meya, David B, Moyo, Melanie, Ssebambulidde, K, Moyo, M., Ndhlovu, CE, Comins, K., Lalloo, David; id_orcid, Molloy, Síle, Singh, Achita, Jjunju, S., Meya, D. B., Kagimu, E., Molloy, Sile F, Moyo, M, Hosseinipour, Mina, Boyer-Chammard, T, Molloy, Síle F, Ssebambulidde, K., Singh, A., Kanyama, Cecilia, Ndhlovu, Chiratidzo E, Kasibante, J, Lalloo, DG, Ndhlovu, C. E., Rutakingirwa, Morris K, Schutz, C, Ssebambulidde, Kenneth, Tugume, L., Ndhlovu, Chiratidzo, Nuwagira, E, Ambition Study Group, Mwandumba, Henry C, Kagimu, E, Muzoora, C, Schutz, C., Boulware, DR, Loyse, Angela, Mzinganjira, H, Hlupeni, A., Jarvis, Joseph N, Kanyama, C, Meya, DB, Chen, T, Chawinga, Chimwemwe, Boyer-Chammard, T., Wang, Duolao, Lawrence, David S, Rhein, Joshua, Molloy, S. F., Siamisang, K, Boulware, David, van Widenfelt, E, Loyse, A, Meintjes, G., Leeme, T., Jaffar, S, Chawinga, C., Molloy, SF, Schutz, Charlotte, Mpoza, E, Youssouf, Nabila, Lortholary, O. +136 morecore +1 more sourceLiposomal amphotericin B as a treatment for human leishmaniasis
, 2012 INTRODUCTION: Leishmaniasis is a parasitic disease transmitted by phlebotomine sandflies. Between 700,000 and 1.2 million cases of cutaneous leishmaniasis and between 200,000 and 400,000 cases of visceral leishmaniasis (VL), which is fatal if left ...Potet, Julien, Gaspani, Sara, Ritmeijer, Koert, Ortiz Genovese, Gemma, Balasegaram, Manica, Lima, Maria Angeles, Burza, Sakib, Milani, Barbara, Chappuis, François +8 morecore +1 more sourceNoncovalent complexation of amphotericin-B with Poly(α-glutamic acid).
, 2013 A noncovalent complex of amphotericin B (AmB) and poly(α-glutamic acid) (PGA) was prepared to develop a safe and stable formulation for the treatment of leishmaniasis. The loading of AmB in the complex was in the range of ∼20-50%.Croft, Simon L, Mohamed-Ahmed, Abeer HA, Simon L. Croft, Les, Karolina A, Karin Seifert, Seifert, Karin, Brocchini, Stephen, Stephen Brocchini, Abeer H. A. Mohamed-Ahmed, Karolina A. Les +9 morecore +1 more sourceUse of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy
Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham +2 morewiley +1 more sourceLimited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence.
, 2011 Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients in Ethiopia who were severely ill or positive for human ...Davidson, Robert N, E. M. Aderie, R. N. Davidson, Collin, Simon M, ter Horst, Rachel, Aderie, EM, ter Horst, R, K. Ritmeijer, Collin, SM, S. Chane, Piening, Turid, Piening, T, Chane, Solomon, Chane, S, T. Piening, Ritmeijer, Koert, Aderie, Endashaw Mengistu, R. ter Horst, Davidson, RN, Ritmeijer, K, S. M. Collin +20 morecore +1 more source
