Results 21 to 30 of about 12,296,614 (200)

Liposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India [PDF]

, 2011
Reports on treatment outcomes of visceral leishmaniasis (VL)-human immunodeficiency virus (HIV) coinfection in India are lacking. To our knowledge, none have studied the efficacy of liposomal amphotericin B in VL-HIV coinfection.
Pece, Manuel, Flevaud, L., Mahajan, Raman, Remartinez, D., Das, Pradeeb, Verma, Neena, Kumar, Nawin, Remartinez, Daniel, M. Pece, Ferreyra, Cecilia, Mitra, G., G. Mitra, N. Verma, Ferreyra, C., Pandey, K., Das, P., van Griensven, Johan, K. Pandey, R. Kumar, R. Mahajan, Mahajan, R., Pandey, Krishna, Kumar, Ranjeet, Mitra, Gaurab, Pece, M., P. P. Palma, Verma, N., P. Das, Kumar, Pankaj, Kumar, N., C. Ferreyra, D. Remartinez, Kumar, P., N. Kumar, Sinha, Prabhat K, Kumar, R., P. K. Sinha, van Griensven, J., Palma, P. P., Sinha, P. K., P. Kumar, Flevaud, Laurence, Palma, Pedro Pablo, J. van Griensven, L. Flevaud   +44 more
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Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days. [PDF]

, 2014
Cryptococcal meningoencephalitis is an urgent global health problem. Induction regimens using 14 days of amphotericin B deoxycholate (dAmB) are considered the standard of care but may not be suitable for resource-poor settings.
Sharp, Andrew D, Andrew D. Sharp, Julie A. Schwartz, Gregson, Lea, Howard, Susan J, Goodwin, Joanne, Susan J. Howard, Bill Moser, John R. Perfect, Müller, W, Sharp, AD, Joanne Goodwin, Moser, Bill, Walker, Catherine, Hope, William W, Lea Gregson, Hope, WW, Perfect, John R, Joanne Livermore, Werner Müller, Schwartz, JA, William W. Hope, Felton, Timothy; id_orcid, Timothy Felton, Catherine Walker, Livermore, J, Schwartz, Julie A, Gregson, L, Goodwin, J, Harrison, Thomas S, Livermore, Joanne, Howard, SJ, Felton, T, Harrison, TS, Walker, C, Perfect, JR, Thomas S. Harrison, Müller, Werner; id_orcid, Moser, B   +38 more
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AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
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Liposomal amphotericin B as a treatment for human leishmaniasis [PDF]

, 2012
INTRODUCTION: Leishmaniasis is a parasitic disease transmitted by phlebotomine sandflies. Between 700,000 and 1.2 million cases of cutaneous leishmaniasis and between 200,000 and 400,000 cases of visceral leishmaniasis (VL), which is fatal if left ...
Potet, Julien, Gaspani, Sara, Ritmeijer, Koert, Ortiz Genovese, Gemma, Balasegaram, Manica, Lima, Maria Angeles, Burza, Sakib, Milani, Barbara, Chappuis, François   +8 more
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Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
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Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence. [PDF]

, 2011
Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients in Ethiopia who were severely ill or positive for human ...
Davidson, Robert N, E. M. Aderie, R. N. Davidson, Collin, Simon M, ter Horst, Rachel, Aderie, EM, ter Horst, R, K. Ritmeijer, Collin, SM, S. Chane, Piening, Turid, Piening, T, Chane, Solomon, Chane, S, T. Piening, Ritmeijer, Koert, Aderie, Endashaw Mengistu, R. ter Horst, Davidson, RN, Ritmeijer, K, S. M. Collin   +20 more
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Safety and usefulness of nebulized liposomal amphotericin B: Systematic scoping review [PDF]

, 2023
Purpose Invasive fungal infections potentially result in fatal outcomes in immunocompromised hosts. Compared to intravenous administration, a nebulization therapy can achieve a high concentration of drug delivered in the respiratory tract, without a ...
Hagiya, Hideharu, Otsuka, Fumio, Nishimura, Yoshito   +2 more
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Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis

Medical Mycology Case Reports, 2017
A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy.
Testuro Ochi, Yuta Katayama, Takeshi Okatani, Ryota Imanaka, Kohei Kyo, Mitsuhiro Itagaki, Shinya Katsutani, Koji Iwato, Hideki Asaoku   +8 more
doaj   +1 more source

Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis [PDF]

, 2014
Invasive pulmonary mucormycosis is a life-threatening fungal infection encountered in immunocompromised patients. An intravenous high-dose lipid formulation of amphotericin B, such as liposomal amphotericin B (L-AMB), is the recommended treatment.
Kakeya, Hiroshi, Imamura, Yoshifumi, Obata, Yoko, Miyazaki, Taiga, Takazono, Takahiro, Nishino, Tomoya, Yamamoto, Yoshihiro, Yanagihara, Katsunori, Kohno, Shigeru, Tsukamoto, Misuzu, Nakamura, Shigeki, Izumikawa, Koichi, Mihara, Tomo, Kurihara, Shintaro, 三原, 智, Tashiro, Takayoshi, Kosai, Kosuke, Morinaga, Yoshitomo   +17 more
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Potency and stability of liposomal Amphotericin B formulated for topical management of Aspergillus spp. infections in burn patients

Burns Open, 2020
Background: Systemic fungal infections are an important mortality factor when considering severely burned patients. Preventive topical pharmacotherapeutic management of deep fungal infections remains of secondary concern when initially treating a burn ...
Alexis Laurent, Olivier Pantet, Lydie Laurent, Nathalie Hirt-Burri, Anthony de Buys Roessingh, Wassim Raffoul, Philippe Laurent, Michel Monod, Lee Ann Applegate   +8 more
doaj   +1 more source