Results 41 to 50 of about 13,126,675 (165)

Deep Dermatophytosis Associated With Inherited CARD9 Deficiency: Efficacy of Topical 1% Voriconazole

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Deep dermatophytosis (DD) is a rare, life‐threatening fungal infection associated with autosomal recessive CARD9 deficiency. Management remains challenging, as systemic antifungals often fail to achieve lasting control. A 54‐year‐old man with a 20‐year history of ulcerative skin lesions and confirmed CARD9 deficiency (Q289X/Q289X) presented ...
Sarah Milesi   +6 more
wiley   +1 more source

Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis [PDF]

open access: yes, 2014
Invasive pulmonary mucormycosis is a life-threatening fungal infection encountered in immunocompromised patients. An intravenous high-dose lipid formulation of amphotericin B, such as liposomal amphotericin B (L-AMB), is the recommended treatment.
Kakeya, Hiroshi   +17 more
core   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija   +6 more
wiley   +1 more source

A difficult-to-treat pleuropulmonary histoplasmosis in a patient with rheumatoid arthritis in Taiwan

open access: yesJournal of Microbiology, Immunology and Infection, 2023
Amphotericin B and itraconazole are the primary agents for treating histoplasmosis. Newer azoles are alternatives for patients refractory to or intolerant of standard therapy.
Wen-Kai Chu   +6 more
doaj   +1 more source

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

open access: yesInternal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley   +15 more
wiley   +1 more source

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

open access: yesMedical Mycology Case Reports, 2018
We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis.
Daiki Karigane   +6 more
doaj   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg   +10 more
wiley   +1 more source

Evaluation of the efficacy, safety and economy of different amphotericin B formulations in invasive fungal disease: A retrospective cohort study

open access: yesPrecision Medication
Background: Fungal infections have emerged as an increasingly serious public health challenge globally. Four Formulations of amphotericin B are widely used in antifungal therapy.
Shuai Liu   +7 more
doaj   +1 more source

Rhinocerebral zygomycosis treated with liposomal amphotericin B and surgery

open access: yes, 2021
We report three cases with rhinocerebral zygomycosis in two diabetic persons and one otherwise healthy person. The diagnosis was established by histopathological appearance and computerized tomography (CT) and/or magnetic resonance imaging (MRI) scans ...
Dundar, IH   +3 more
core   +2 more sources

Real‐World Survival Outcomes of Venetoclax Combination Therapies in Acute Myeloid Leukemia: Impact of Minimal Residual Disease Status and Antifungal Prophylaxis

open access: yesHematological Oncology, Volume 44, Issue 6, November 2026.
ABSTRACT In recent years the addition of the oral BCL2 inhibitor venetoclax to hypomethylating agents (HMAs) has emerged as the standard‐of‐care for patients with acute myeloid leukemia (AML) who are not fit for intensive chemotherapy, significantly improving survival and quality‐of‐life.
Mariarita Sciumè   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy