Results 101 to 110 of about 104,641 (308)
DigitalBackground: Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Morales López, Soraya +10 more
core +1 more source
Short nanofiber fragments (SNFs) derived from electrospun PDLA/gelatin (PG) mats dynamically reassemble into conformal fibrous networks on complex substrates. This approach overcomes the geometric limitations of conventional electrospinning, enabling uniform surface coverage, enhanced wettability, and cytocompatible scaffold formation, thereby offering
Iruthayapandi Selestin Raja +7 more
wiley +1 more source
Molecular Modeling Studies on Amphotericin B and its Complex with Phospholipid,
Molecular dynamics simulation studies on polyene antifungal antibiotic amphotericin B, its head-to-tail dimeric structure and lipid - amphotericin B complex demonstrate interesting features of the flexibilities within the molecule and define the optimal ...
Easwaran, KRK +4 more
core
SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà +10 more
wiley +1 more source
Jun Ye,1,2 Renjie Li,1,2 Jialing Cheng,1,2 Dongdong Liu,1,2 Yanfang Yang,1,2 Hongliang Wang,1,2 Xiaoyan Xu,1,2 Lin Li,1,2 Panpan Ma,3 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia ...
Ma P +9 more
core
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo +16 more
wiley +1 more source
The distribution of amphotericin B in lung tissue was studied in 18 patients with primary or secondary lung cancer who underwent thoracotomy and pulmonary resection.
F. Fraschini +4 more
core +1 more source
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó +9 more
wiley +1 more source
Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An +7 more
wiley +1 more source
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija +6 more
wiley +1 more source

