Results 101 to 110 of about 104,641 (308)

Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris

open access: yes, 2019
DigitalBackground: Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Morales López, Soraya   +10 more
core   +1 more source

Injectable Short Nanofiber Fragments Enable Conformal Fibrous Scaffolds for Tissue Engineering on Complex Surfaces

open access: yesMacromolecular Rapid Communications, EarlyView.
Short nanofiber fragments (SNFs) derived from electrospun PDLA/gelatin (PG) mats dynamically reassemble into conformal fibrous networks on complex substrates. This approach overcomes the geometric limitations of conventional electrospinning, enabling uniform surface coverage, enhanced wettability, and cytocompatible scaffold formation, thereby offering
Iruthayapandi Selestin Raja   +7 more
wiley   +1 more source

Molecular Modeling Studies on Amphotericin B and its Complex with Phospholipid,

open access: yes, 1995
Molecular dynamics simulation studies on polyene antifungal antibiotic amphotericin B, its head-to-tail dimeric structure and lipid - amphotericin B complex demonstrate interesting features of the flexibilities within the molecule and define the optimal ...
Easwaran, KRK   +4 more
core  

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

Comparative Colloidal Stability of Commercial Amphotericin B Nanoformulations Using Dynamic and Static Multiple Light Scattering Techniques

open access: yes, 2022
Jun Ye,1,2 Renjie Li,1,2 Jialing Cheng,1,2 Dongdong Liu,1,2 Yanfang Yang,1,2 Hongliang Wang,1,2 Xiaoyan Xu,1,2 Lin Li,1,2 Panpan Ma,3 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia ...
Ma P   +9 more
core  

The Allium cepa Derived Compound Propyl Propane Thiosulfonate (PTSO) Improves Tumorigenesis Due to Its Immunomodulatory Effect: A Preclinical Study

open access: yesPhytotherapy Research, EarlyView.
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo   +16 more
wiley   +1 more source

Penetration of amphotericin B in human lung tissue after single liposomal amphotericin B (AmBisome) infusion

open access: yes, 2005
The distribution of amphotericin B in lung tissue was studied in 18 patients with primary or secondary lung cancer who underwent thoracotomy and pulmonary resection.
F. Fraschini   +4 more
core   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó   +9 more
wiley   +1 more source

Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An   +7 more
wiley   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy