In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis
The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin B ...
Benedikt Göttel +7 more
doaj +1 more source
Successful treatment of subcutaneously disseminated aspergillosis with caspofungin acetate in an allogeneic peripheral blood stem cell transplantation patient. [PDF]
We present a patient with acute myeloid leukaemia who developed subcutaneously disseminated aspergillosis after allogeneic peripheral stem cell transplantation (PSCT).
Chamuleau, M.E.D. +5 more
core +1 more source
Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba +3 more
core +1 more source
Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li +8 more
wiley +1 more source
Intestinal fungi contribute to development of alcoholic liver disease [PDF]
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian +37 more
core +3 more sources
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro +3 more
wiley +1 more source
Background: Invasive mucormycosis (IM) poses a substantial morbidity and mortality burden among immunocompromised patients. Objectives: We aim to compare the real-world effectiveness and safety of isavuconazole with those of amphotericin B in patients ...
Jiayuan Qin +6 more
doaj +1 more source
Antifungal Activity of Silver Nanoparticles, Copper Nanoparticles, Their Combination and with Amphotericin B against Candida glabrata In vitro and In vivo [PDF]
Background: Candida glabrata is the fourth most common cause of blood infection in America and, due to its resistance to amphotericin B, we have to look for new therapies.
Mahdi Jafarzadeh +2 more
doaj
The Inhibitory Effect of Validamycin A on Aspergillus flavus
Aspergillus flavus is one of the most common isolates from patients with fungal infections. Aspergillus infection is usually treated with antifungal agents, but side effects of these agents are common.
Napasawan Plabutong +6 more
doaj +1 more source
Electrophysiological characteristics of cationic single-channel formed by incorporation of amphotericin b in bilayer lipid membrane [PDF]
BACKGROUND AND OBJECTIVE: Amphotericin B (AmB) is the main antibiotic of polyene type, which is widely used in the treatment of systemic fungal infections.
Ashrafpour, M. +2 more
core

