Results 61 to 70 of about 104,641 (308)

Use of amphotericin B.

, 2013
Amphotericin B formulation trends over time. Annual percentage of patients receiving lipid formulation amphotericin B (LF AmpB) or deoxycholate amphotericin B (AmpBd) for initial therapy (N = 132).
Nada El Husseini (310362), Charles Poole (71733), Til Stürmer (310364), Cody A. Chastain (310363), David J. Weber (15006), John R. Perfect (82075), Emily W. Bratton (310361), Michael S. Lee (220943), Jonathan J. Juliano (310365)   +8 more
core   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Liposomal amphotericin B as a treatment for human leishmaniasis

, 2012
INTRODUCTION: Leishmaniasis is a parasitic disease transmitted by phlebotomine sandflies. Between 700,000 and 1.2 million cases of cutaneous leishmaniasis and between 200,000 and 400,000 cases of visceral leishmaniasis (VL), which is fatal if left ...
Potet, Julien, Gaspani, Sara, Ritmeijer, Koert, Ortiz Genovese, Gemma, Balasegaram, Manica, Lima, Maria Angeles, Burza, Sakib, Milani, Barbara, Chappuis, François   +8 more
core   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report

Revista da Sociedade Brasileira de Medicina Tropical, 2019
In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate.
Benivaldo Ramos Ferreira Terceiro, Tania Salgado de Souza Torraca, Frederico Pereira Bom Braga, Ana Cristina da Costa Martins, Lucia Regina Brahim, Mauricio Naoto Saheki, Luciana de Freitas Campos Miranda, Armando de Oliveira Schubach, Cláudia Maria Valete-Rosalino   +8 more
doaj   +1 more source

Disseminated Histoplasmosis in HIV-Infected Patients: A Description of 34 Years of Clinical and Therapeutic Practice

Journal of Fungi, 2020
Disseminated histoplasmosis is the main AIDS-defining infection of French Guiana. We aim to describe our therapeutic experience for 349 patients with disseminated histoplasmosis between 1 January 1981 and 10 January 2014 in French Guiana.
Mathieu Nacher, Audrey Valdes, Antoine Adenis, Romain Blaizot, Philippe Abboud, Magalie Demar, Félix Djossou, Loïc Epelboin, Caroline Misslin, Balthazar Ntab, Kinan Drak Alsibai, Pierre Couppié   +11 more
doaj   +1 more source

Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis

, 2014
Invasive pulmonary mucormycosis is a life-threatening fungal infection encountered in immunocompromised patients. An intravenous high-dose lipid formulation of amphotericin B, such as liposomal amphotericin B (L-AMB), is the recommended treatment.
Kakeya, Hiroshi, Imamura, Yoshifumi, Obata, Yoko, Miyazaki, Taiga, Takazono, Takahiro, Nishino, Tomoya, Yamamoto, Yoshihiro, Yanagihara, Katsunori, Kohno, Shigeru, Tsukamoto, Misuzu, Nakamura, Shigeki, Izumikawa, Koichi, Mihara, Tomo, Kurihara, Shintaro, 三原, 智, Tashiro, Takayoshi, Kosai, Kosuke, Morinaga, Yoshitomo   +17 more
core   +1 more source

First report of amphotericin B resistant Candida haemulonii isolated from the ICU of a referral hospital in Indonesia

Iranian Journal of Microbiology
Background and Objectives: Amphotericin B is a broad-spectrum antifungal agent commonly used to treat Candida haemulonii infection. C. haemulonii was isolated from patients reported to be intrinsically resistant to amphotericin B, encoded by the ERG2 ...
Rifdah Hanifah, Mardiastuti Wahid, Andi Yasmon   +2 more
doaj   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Emma F. Barry, Lindsay Durr, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source