Results 41 to 50 of about 13,189,470 (203)

Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis

Acta Dermato-Venereologica, 2022
The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis.
Michal Solomon, Shoshana Greenberger, Maya Milner, Felix Pavlotzky, Aviv Barzilai, Eli Schwartz, Noa Hadayer, Sharon Baum   +7 more
doaj   +1 more source

Amphotericin B-impregnated bone cement to treat refractory coccidioidal osteomyelitis. [PDF]

, 2013
Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection.
Giza, Eric, Zhu, Elizabeth S, Kreulen, Christopher, Thompson, George R   +3 more
core   +1 more source

Amphotericin B Pharmacokinetics During Extracorporea/Membrane Oxygenation: A Case Report

, 2023
Amphotericin B treatment during extracorporeal membrane oxygenation is at times necessary for the treatment of secondary fungemia or, less commonly, to treat a primary fungal infection.
James H. Hertzog, Mark Sale, Gabriel J. Hauser, Ellen Brackett, Heidi J. Dalton   +4 more
core   +1 more source

Efficacy of aerosolized amphotericin B desoxycholate and liposomal amphotericin B in the treatment of invasive pulmonary aspergillosis in severely immunocompromised rats [PDF]

, 2001
The effects of treatment with aerosolized amphotericin B desoxycholate and aerosolized liposomal amphotericin B were evaluated in severely immunosuppressed rats with invasive pulmonary aspergillosis.
Ruijgrok, E.J. (Elisabeth), Vulto, A.G. (Arnold), Etten, E.W.M. (Els) van, Van Etten, Els W.M., Ruijgrok, Elisabeth J.; id_orcid, Vulto, Arnold G.; id_orcid   +5 more
core   +2 more sources

Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance

Pharmaceutics, 2022
Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its delivery orally.
Shadreen Fairuz, Rajesh Sreedharan Nair, Nashiru Billa   +2 more
doaj   +1 more source

Retrobulbar Injection of Amphotericin B in the Management of Acute Invasive Fungal Sino-Orbital Infections

, 2023
Objective: Treatment for acute invasive fungal rhinosinusitis consists of systemic antifungal therapy, early and aggressive surgical debridement, and reversal of immunosuppression.
V. Ninclaus, T. Van Zele, Coppens, Marc, M. De Kezel, M. Coppens, Van Zele, Thibaut, De Kezel, Margot, Ninclaus, Virginie   +7 more
core   +1 more source

Experience of research nurses with oral encochleated amphotericin B for treatment of cryptococcal meningitis in a resource-limited setting

BMC Infectious Diseases
Background Besides the commonly used intravenous formulations of amphotericin B, an oral nanocrystal amphotericin B (MAT2203) formulation is being evaluated for efficacy to treat invasive fungal infections.
Cynthia Ahimbisibwe, Richard Kwizera, Jane Frances Ndyetukira, Olivie Carolyne Namujju, Alisat Sadiq, Mucunguzi Atukunda, Caleb P. Skipper, David R. Boulware, David B. Meya   +8 more
doaj   +1 more source

Quercetin and rutin as potential agents antifungal against Cryptococcus spp

Brazilian Journal of Biology
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study
V. M. Oliveira, E. Carraro, M. E. Auler, N. M. Khalil   +3 more
doaj   +1 more source

Delayed results of treatment of paracoccidioidomycosis with amphotericin B plus sulfamides versus amphotericin B alone

Revista do Instituto de Medicina Tropical de São Paulo, 1986
A delayed evaluation of two groups of patients with paracoccidioidomycosis was carried out. Both groups were treated with amphotericin B, "but one of them was submitted to maintenance treatment with sulfonamides.
Neuza Lima Dillon, Sebastião A. P. Sampaio, Marta Cassoni Habermann, Silvio Alencar Marques, Joel Carlos Lastória, Hamilton Ometto Stolf, Nilson Camargo de Andrade Selva, Paulo Roberto Curi   +7 more
doaj   +1 more source

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
core   +2 more sources