Results 51 to 60 of about 148,552 (285)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Experience of research nurses with oral encochleated amphotericin B for treatment of cryptococcal meningitis in a resource-limited setting

BMC Infectious Diseases
Background Besides the commonly used intravenous formulations of amphotericin B, an oral nanocrystal amphotericin B (MAT2203) formulation is being evaluated for efficacy to treat invasive fungal infections.
Cynthia Ahimbisibwe, Richard Kwizera, Jane Frances Ndyetukira, Olivie Carolyne Namujju, Alisat Sadiq, Mucunguzi Atukunda, Caleb P. Skipper, David R. Boulware, David B. Meya   +8 more
doaj   +1 more source

Quercetin and rutin as potential agents antifungal against Cryptococcus spp

Brazilian Journal of Biology
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study
V. M. Oliveira, E. Carraro, M. E. Auler, N. M. Khalil   +3 more
doaj   +1 more source

Delayed results of treatment of paracoccidioidomycosis with amphotericin B plus sulfamides versus amphotericin B alone

Revista do Instituto de Medicina Tropical de São Paulo, 1986
A delayed evaluation of two groups of patients with paracoccidioidomycosis was carried out. Both groups were treated with amphotericin B, "but one of them was submitted to maintenance treatment with sulfonamides.
Neuza Lima Dillon, Sebastião A. P. Sampaio, Marta Cassoni Habermann, Silvio Alencar Marques, Joel Carlos Lastória, Hamilton Ometto Stolf, Nilson Camargo de Andrade Selva, Paulo Roberto Curi   +7 more
doaj   +1 more source

Impact of antibiotics on the proliferation and differentiation of human adipose-derived mesenchymal stem cells [PDF]

, 2017
Adipose tissue is a promising source of mesenchymal stem cells. Their potential to differentiate and regenerate other types of tissues may be affected by several factors. This may be due to in vitro cell-culture conditions, especially the supplementation
Gola, Joanna, Hybiak, Jolanta, Mazurek, Urszula, Paul-Samojedny, Monika, Sikora, Bartosz, Skubis, Aleksandra, Łos, Marek   +6 more
core   +4 more sources

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B

Journal of Orthopaedic Surgery and Research
Background Amphotericin is admixed to Polymethylmethacrylic (PMMA) spacers for fungal periprosthetic joint infections (PJI) during two-stage exchanges. We aimed to analyse the mechanical properties of PMMA cement with admixed Amphotericin B.
Florian A. Frank, Barbara Krampitz, Julia Steiner, Rainer Strathausen, Mario Morgenstern, Martin Clauss, Klaus-Dieter Kühn   +6 more
doaj   +1 more source

Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance

Pharmaceutics, 2022
Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its delivery orally.
Shadreen Fairuz, Rajesh Sreedharan Nair, Nashiru Billa   +2 more
doaj   +1 more source

Anfotericina B forma liposómica: un perfil farmacocinético exclusivo. Una historia inacabada. [PDF]

, 2012
Amphotericin B in its lipid formulation continues to be the reference drug in the treatment of systemic fungal infections despite the time elapse since the development of this compound.
Azanza, J.R. (José Ramón), Barberan, J. (Jose)   +1 more
core  

Rhinocerebral mucormycosis treated with 32 gram liposomal amphotericin B and incomplete surgery: a case report [PDF]

, 2001
Background Mucormycosis (or zygomycosis) is the term for infection caused by fungi of the order Mucorales. Mucoraceae may produce severe disease in susceptible individuals, notably patients with diabetes and leukemia.
MG Rinaldi, R Koçak, D Selcen, S Maury, AM Sugar, NA Parfrey, KK Lim, M Ericsson, HA Gallis, F Meunier, J Brajtburg, H Funada, AE Moses, S Kline, TJ Walsh   +14 more
core   +2 more sources