Results 51 to 60 of about 12,359,869 (300)

Experience of research nurses with oral encochleated amphotericin B for treatment of cryptococcal meningitis in a resource-limited setting

BMC Infectious Diseases
Background Besides the commonly used intravenous formulations of amphotericin B, an oral nanocrystal amphotericin B (MAT2203) formulation is being evaluated for efficacy to treat invasive fungal infections.
Cynthia Ahimbisibwe, Richard Kwizera, Jane Frances Ndyetukira, Olivie Carolyne Namujju, Alisat Sadiq, Mucunguzi Atukunda, Caleb P. Skipper, David R. Boulware, David B. Meya   +8 more
doaj   +1 more source

Quercetin and rutin as potential agents antifungal against Cryptococcus spp

Brazilian Journal of Biology
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study
V. M. Oliveira, E. Carraro, M. E. Auler, N. M. Khalil   +3 more
doaj   +1 more source

Delayed results of treatment of paracoccidioidomycosis with amphotericin B plus sulfamides versus amphotericin B alone

Revista do Instituto de Medicina Tropical de São Paulo, 1986
A delayed evaluation of two groups of patients with paracoccidioidomycosis was carried out. Both groups were treated with amphotericin B, "but one of them was submitted to maintenance treatment with sulfonamides.
Neuza Lima Dillon, Sebastião A. P. Sampaio, Marta Cassoni Habermann, Silvio Alencar Marques, Joel Carlos Lastória, Hamilton Ometto Stolf, Nilson Camargo de Andrade Selva, Paulo Roberto Curi   +7 more
doaj   +1 more source

Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance

Pharmaceutics, 2022
Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its delivery orally.
Shadreen Fairuz, Rajesh Sreedharan Nair, Nashiru Billa   +2 more
doaj   +1 more source

Antileishmanial activity of nano-amphotericin B deoxycholate [PDF]

, 2008
Objectives The aim of the present study was to compare the efficacy of a nano form of amphotericin B deoxycholate with that of conventional amphotericin B deoxycholate for the treatment of visceral leishmaniasis. Methods We have formulated nanoparticles
Rai, Madhukar, T. P. Yadav, Kumar, Subodh, M. Rai, Dube, Anuradha, Yadav, Thakur Prasad, A. Dube, Prajapati, Vijay Kumar, K. D. Manandhar, V. K. Prajapati, Manandhar, Krishna Das, Sundar, Shyam, O. N. Srivastava, Srivastava, Onkar Nath, S. Kumar, S. Sundar   +15 more
core   +1 more source

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

Advanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet, Hao Ye, Abderrahim Lahlahi Attalhaoui, Donghoon Kim, Vitaly Pustovalov, Elric Zhang, Marc Tudela‐Pi, Bastian Gebauer, Juan Bautista Carda Castelló, Anton Guimerà‐Brunet, Josep Puigmartí‐Luis, Xiang‐Zhong Chen, Minsoo Kim, Salvador Pané   +13 more
wiley   +1 more source

Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice [PDF]

, 2011
Nan Xu1,2, Julin Gu3, Yuanjie Zhu3, Hai Wen3, Qiushi Ren1, Jianghan Chen31Institute for Laser Medicine and Biophotonics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People's Republic of China; 2Department ...
Wen H, null Xu, Zhu Yuanjie, Xu N, Gu Julin, Wen Hai, Ren QS, Zhu YJ, Ren Qiushi, Gu JL, Chen Jianghan, Chen JH   +11 more
core   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B

Journal of Orthopaedic Surgery and Research
Background Amphotericin is admixed to Polymethylmethacrylic (PMMA) spacers for fungal periprosthetic joint infections (PJI) during two-stage exchanges. We aimed to analyse the mechanical properties of PMMA cement with admixed Amphotericin B.
Florian A. Frank, Barbara Krampitz, Julia Steiner, Rainer Strathausen, Mario Morgenstern, Martin Clauss, Klaus-Dieter Kühn   +6 more
doaj   +1 more source

Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence. [PDF]

, 2011
Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients in Ethiopia who were severely ill or positive for human ...
Davidson, Robert N, E. M. Aderie, R. N. Davidson, Collin, Simon M, ter Horst, Rachel, Aderie, EM, ter Horst, R, K. Ritmeijer, Collin, SM, S. Chane, Piening, Turid, Piening, T, Chane, Solomon, Chane, S, T. Piening, Ritmeijer, Koert, Aderie, Endashaw Mengistu, R. ter Horst, Davidson, RN, Ritmeijer, K, S. M. Collin   +20 more
core   +1 more source