Results 71 to 80 of about 104,641 (308)

Antibiotics and antifungals in silicone oil

International Journal of Retina and Vitreous, 2019
Background Antimicrobials may be injected into silicone oil-filled eyes with endophthalmitis, but the interaction with oil is unclear. The purpose of the experiment is to determine whether vancomycin, amikacin, and amphotericin B mix with silicone oil ...
Ella H. Leung, J. Timothy Stout
doaj   +1 more source

The Inhibitory Effect of Validamycin A on Aspergillus flavus

International Journal of Microbiology, 2020
Aspergillus flavus is one of the most common isolates from patients with fungal infections. Aspergillus infection is usually treated with antifungal agents, but side effects of these agents are common.
Napasawan Plabutong, Supanuch Ekronarongchai, Nattarika Niwetbowornchai, Steven W. Edwards, Sita Virakul, Direkrit Chiewchengchol, Arsa Thammahong   +6 more
doaj   +1 more source

In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis

Frontiers in Bioengineering and Biotechnology, 2020
The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin B ...
Benedikt Göttel, Henrike Lucas, Frank Syrowatka, Wolfgang Knolle, Judith Kuntsche, Joana Heinzelmann, Arne Viestenz, Karsten Mäder   +7 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Real-World Effectiveness and Safety of Isavuconazole Versus Amphotericin B for Patients with Invasive Mucormycosis

Microorganisms
Background: Invasive mucormycosis (IM) poses a substantial morbidity and mortality burden among immunocompromised patients. Objectives: We aim to compare the real-world effectiveness and safety of isavuconazole with those of amphotericin B in patients ...
Jiayuan Qin, Hongxia Bi, Guangmin Tang, Xinyao Liu, Junyan Qu, Xiaoju Lv, Yanbin Liu   +6 more
doaj   +1 more source

Antileishmanial activity of nano-amphotericin B deoxycholate

, 2008
Objectives The aim of the present study was to compare the efficacy of a nano form of amphotericin B deoxycholate with that of conventional amphotericin B deoxycholate for the treatment of visceral leishmaniasis. Methods We have formulated nanoparticles
Rai, Madhukar, T. P. Yadav, Kumar, Subodh, M. Rai, Dube, Anuradha, Yadav, Thakur Prasad, A. Dube, Prajapati, Vijay Kumar, K. D. Manandhar, V. K. Prajapati, Manandhar, Krishna Das, Sundar, Shyam, O. N. Srivastava, Srivastava, Onkar Nath, S. Kumar, S. Sundar   +15 more
core   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice

, 2011
Nan Xu1,2, Julin Gu3, Yuanjie Zhu3, Hai Wen3, Qiushi Ren1, Jianghan Chen31Institute for Laser Medicine and Biophotonics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People's Republic of China; 2Department ...
Wen H, null Xu, Zhu Yuanjie, Xu N, Gu Julin, Wen Hai, Ren QS, Zhu YJ, Ren Qiushi, Gu JL, Chen Jianghan, Chen JH   +11 more
core   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

Antifungal Activity of Silver Nanoparticles, Copper Nanoparticles, Their Combination and with Amphotericin B against Candida glabrata In vitro and In vivo [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: Candida glabrata is the fourth most common cause of blood infection in America and, due to its resistance to amphotericin B, we have to look for new therapies.
Mahdi Jafarzadeh, Mojtaba Salouti, Rasoul Shokri   +2 more
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