Results 21 to 30 of about 12,359,869 (300)

Do Ophthalmic Solutions of Amphotericin B Solubilised in 2-Hydroxypropyl-γ-Cyclodextrins Possess an Extended Physicochemical Stability?

open access: yesPharmaceutics, 2020
Fungal keratitis is a sight-threatening disease for which amphotericin B eye drops is one of the front-line treatments. Unfortunately, there are currently no commercial forms available, and there is little data concerning the long-term stability of ...
Philip Chennell   +6 more
doaj   +1 more source

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal. [PDF]

open access: yes, 2013
Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice.
A. Loyse   +10 more
core   +1 more source

Liposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India [PDF]

open access: yes, 2011
Reports on treatment outcomes of visceral leishmaniasis (VL)-human immunodeficiency virus (HIV) coinfection in India are lacking. To our knowledge, none have studied the efficacy of liposomal amphotericin B in VL-HIV coinfection.
Pece, Manuel   +44 more
core   +1 more source

Therapeutic potential of Calotropis gigantea extract against invasive pulmonary aspergillosis: In vitro and in vivo study

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2022
Objective: To characterize the antifungal activity of methanolic leaf extract of Calotropis gigantea alone or in combination with amphotericin B against invasive pulmonary aspergillosis in mice. Methods: GC/MS was used for analysis of active constituents
Enas M Ali   +2 more
doaj   +1 more source

Retrobulbar Injection of Amphotericin B in the Management of Acute Invasive Fungal Sino-Orbital Infections

open access: yes, 2023
Objective: Treatment for acute invasive fungal rhinosinusitis consists of systemic antifungal therapy, early and aggressive surgical debridement, and reversal of immunosuppression.
V. Ninclaus   +7 more
core   +1 more source

Amphotericin B-Induced Encephalopathy

open access: yesPediatric Neurology Briefs, 1995
Three children with refractory leukemia treated by bone marrow transplantation at the Children’s National Medical Center, Washington, DC, developed encephalopathy, leukoencephalopathy, and parkinsonism after receiving high-dose amphotericin B for ...
J Gordon Millichap
doaj   +1 more source

Efficacy of combination therapy of amphotericin and posaconazole in treatment of mucormycosis

open access: yesJournal of Applied Pharmaceutical Research, 2023
Background: Mucormycosis is an opportunistic systemic fungal infection which is debilitating caused by order Mucorales. The standard management of mucormycosis consists of aggressive debridement of the infected tissue and parenteral anti-fungal therapy ...
Sridhara S   +4 more
doaj   +1 more source

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

open access: yes, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo   +50 more
core   +2 more sources

Preventing or attenuating amphotericin B nephrotoxicity with dopamine receptor agonists: a literature review [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2015
Nephrotoxicity is generally considered as the most clinically significant and dose-limiting adverse reaction of amphotericin B. Currently, only the clinical effectiveness of salt loading and administering lipid formulations of amphotericin B have been ...
Iman Karimzadeh   +2 more
doaj   +2 more sources

Amphotericin b in vivo hatékonysága candida auris ellen

open access: yes, 2021
Munkánk során azt vizsgáltuk, hogy mennyire ellenálló a Candida auris amphotericin B-vel szemben. Ennek érdekében két földrajzi kládból választottunk törzseket: dél-afrikai és kelet ázsiai.
Tokai-Kiss, Tamás
core  

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