Results 131 to 140 of about 13,097,347 (378)

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh, Cuong Tran‐Manh, Andrea‐Hermina Györfi, Nicholas Dickel, Christoph Liebel, Xiang Zhou, Jiucun Wang, Meik Kunz, Helena Arozenius, Lars Pettersson, Sam Lindgren, Christina Wenglén, Jörg H. W. Distler   +12 more
wiley   +1 more source

Using single-dose liposomal amphotericin B for cryptococcal meningitis induction therapy: nurse pearls and practical perspectives [version 2; peer review: 2 approved]

Wellcome Open Research
Background In Uganda where the burden of HIV-associated cryptococcal meningitis is high, conventional amphotericin B deoxycholate has been standard to manage patients with cryptococcal meningitis in research settings.
Richard Kwizera, Cynthia Ahimbisibwe, Jane Frances Ndyetukira, David B. Meya, Carol Namujju   +4 more
doaj  

Antifungal Agents for the Treatment of Systemic Fungal Infections in Children

Canadian Journal of Infectious Diseases and Medical Microbiology, 2010
Traditionally, the mainstay of systemic antifungal therapy has been amphotericin B deoxycholate (conventional amphotericin B). Newer agents have been developed to fulfill special niches and to compete with conventional amphotericin B by virtue of having ...
UD Allen
doaj   +1 more source

Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes [PDF]

, 2015
The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous ...
Adamcik, Aggeli, Asher, Assenza, Barratt, Cybulska, Davis, de Kruijf, de Kruijf, Foglia, Foglia, Gaboriau, Gagoś, Gallis, Grijalba, Gruszecki, Gruszecki, Gruziel, Herec, Ian William Hamley, Janne Ruokolainen, Kang, Lamyfreund, Mazerski, McNamara, Mehedi Reza, Milhaud, Mohamed-Ahmed, Murphy, Nyrkova, Nyrkova, O'Neil, Petit, Radoslaw M. Kowalczyk, Sanchez-Brunete, Starzyk, Steven Kirkham, Torrado, Usov, Valeria Castelletto, Vandeputte, Wasko   +41 more
core   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

The role of oxidative and nitrosative bursts caused by azoles and amphotericin B against the fungal pathogen Cryptococcus gattii.

Journal of Antimicrobial Chemotherapy, 2013
OBJECTIVES Although the most accepted mechanisms of action of amphotericin B and azoles are related to ergosterol, it is possible that these drugs have other effects on the fungal cell. In the present study, the role of endogenous reactive oxygen species
G. Ferreira, Ludmila M. Baltazar, J. R. Santos, A. S. Monteiro, L. Fraga, M. A. Resende-Stoianoff, D. A. Santos   +6 more
semanticscholar   +1 more source

Successful treatment of subcutaneously disseminated aspergillosis with caspofungin acetate in an allogeneic peripheral blood stem cell transplantation patient. [PDF]

, 2003
We present a patient with acute myeloid leukaemia who developed subcutaneously disseminated aspergillosis after allogeneic peripheral stem cell transplantation (PSCT).
Chamuleau, M.E.D., Deenik, W., Janssen, J.J.W.M., Jonkhoff, A.R., Zaaijer, H.L., Zweegman, S.   +5 more
core   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

In vitro ultrastructure and biodegradation of activated plasma albumin gel derived from human samples: A prospective observational study

Clinical Advances in Periodontics, EarlyView.
Abstract Background In soft tissue regeneration, the clinical efficacy of fibrin membranes has been a pressing concern. The key to this efficacy lies in the stability of membrane and its controlled absorption. Human serum albumin, with its influence on the formation and stability of fibrin networks, could hold the key to developing a more stable ...
Behzad Houshmand, Mohammadreza Talebi Ardakani, Farshad Armandei, Anahita Moscowchi, Ahmad Nazari, Jafar Ai, Mehdi Ekhlasmand Kermani, Hamoun Sabri   +7 more
wiley   +1 more source

The Effect of Amphotericin B on the Water and Nonelectrolyte Permeability of Thin Lipid Membranes [PDF]

, 1969
Thomas E. Andreoli, Vincent W. Dennis, Ann M. Weigl   +2 more
openalex   +1 more source