Results 131 to 140 of about 95,889 (290)

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

open access: yesAllergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek   +7 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

Effect of liposomal amphotericin B on murine macrophages and lymphocytes [PDF]

open access: bronze, 1985
R T Mehta   +3 more
openalex   +1 more source

The epidemiological landscape of bloodstream infections in children undergoing chemotherapy or haematopoietic cell transplantation: A retrospective study by Infectious Diseases Working Group of Italian Association of Pediatric Hematology and Oncology (AIEOP)

open access: yesBritish Journal of Haematology, EarlyView.
Summary Understanding bloodstream infection (BSI) epidemiology is crucial for optimizing antibiotic therapy in paediatric haematology–oncology patients undergoing chemotherapy or haematopoietic cell transplantation (HCT). However, updated paediatric data remain scarce.
Francesco Baccelli   +35 more
wiley   +1 more source

Has early mortality following single‐unit unrelated cord blood transplantation improved in recent years? A nationwide registry data analysis from 2003 to 2022 in Japan

open access: yesBritish Journal of Haematology, EarlyView.
The 100‐day non‐relapse mortality after single‐unit cord blood transplantation significantly declined from 19.6% (2003–2007) to 9.5% (2018–2022), while the 3‐year overall survival improved from 38.8% to 54.4%. Haematopoietic recovery rates improved steadily, with neutrophil engraftment reaching 89.6% and platelet engraftment 78.0% in the most recent ...
Takaaki Konuma   +19 more
wiley   +1 more source

Elucidation of the zinc binding site in KCNQ channels

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose KCNQ1‐5 (Kv7.1–7.5) are members of a family of voltage‐gated potassium channels with prominent function in the nervous and cardiovascular systems and in epithelia. KCNQ channels are activated by intracellular free zinc, but the molecular mechanism of this effect is poorly understood and zinc binding sites within KCNQ channels are
Shuo Zhang   +6 more
wiley   +1 more source

Liposomal amphotericin B prophylaxis in paediatrics: a systematic review. [PDF]

open access: yesJ Antimicrob Chemother
Thorley EV   +9 more
europepmc   +1 more source

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