Results 11 to 20 of about 374,595 (258)
Lipase-Responsive Amphotericin B Loaded PCL Nanoparticles for Antifungal Therapies
Nanomaterials, 2022 Amphotericin B is an antifungal drug used for the treatment of invasive fungal infections. However, its clinical use is limited due to its serious side effects, such as renal and cardiovascular toxicity.
Evelyn Osehontue Uroro +3 more
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In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB /c mice [PDF]
Rev. Inst. Med. Trop. Sao Paulo. 2011, 53 (3): 129 - 132, 2011 The in vitro and in vivo activity of diminazene (Dim), artesunate (Art) and combination of Dim and Art (Dim-Art) against Leishmania donovani was compared to reference drug; amphotericin B. IC50 of Dim-Art was found to be $2.28 \pm 0.24 \mu$ g/mL while those of Dim and Art were $9.16 \pm 0.3 \mu$ g/mL and $4.64 \pm 0.48 \mu$ g/mL respectively.
arxiv +1 more source
Онкогематология, 2014 An overview of the literature data concerning the comparison of toxicity, efficacy and cost of amphotericin B lipid complex and liposomal amphotericin B, as well as their comparison with amphotericin B deoxycholate are provided.
N. V. Dmitrieva, I. N. Petukhova
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Pharmaceutics, 2020 Fungal keratitis is a sight-threatening disease for which amphotericin B eye drops is one of the front-line treatments. Unfortunately, there are currently no commercial forms available, and there is little data concerning the long-term stability of ...
Philip Chennell +6 more
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Brazilian Journal of Biology, 2018 Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting immunocompromised patients. However, severe side effects have limited the utility of this drug.
V. M. Oliveira, N. M. Khalil, E. Carraro
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Pharmaceutics, 2021 Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated.
Unai Caballero +3 more
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Amphotericin B-Induced Encephalopathy
Pediatric Neurology Briefs, 1995 Three children with refractory leukemia treated by bone marrow transplantation at the Children’s National Medical Center, Washington, DC, developed encephalopathy, leukoencephalopathy, and parkinsonism after receiving high-dose amphotericin B for ...
J Gordon Millichap
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Asian Pacific Journal of Tropical Biomedicine, 2022 Objective: To characterize the antifungal activity of methanolic leaf extract of Calotropis gigantea alone or in combination with amphotericin B against invasive pulmonary aspergillosis in mice. Methods: GC/MS was used for analysis of active constituents
Enas M Ali +2 more
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Efficacy of combination therapy of amphotericin and posaconazole in treatment of mucormycosis
Journal of Applied Pharmaceutical Research, 2023 Background: Mucormycosis is an opportunistic systemic fungal infection which is debilitating caused by order Mucorales. The standard management of mucormycosis consists of aggressive debridement of the infected tissue and parenteral anti-fungal therapy ...
Sridhara S +4 more
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Preventing or attenuating amphotericin B nephrotoxicity with dopamine receptor agonists: a literature review [PDF]
Trends in Pharmaceutical Sciences, 2015 Nephrotoxicity is generally considered as the most clinically significant and dose-limiting adverse reaction of amphotericin B. Currently, only the clinical effectiveness of salt loading and administering lipid formulations of amphotericin B have been ...
Iman Karimzadeh +2 more
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