Results 191 to 200 of about 91,427 (251)
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Journal of Antimicrobial Chemotherapy, 2002
Abstract The use of amphotericin B limited by dose-dependent nephrotoxicity. Elevated creatinine associated with amphotericin B is not only a marker for renal dysfunction, but is also linked to an increase in hospital costs and a substantial risk for the use of haemodialysis and a higher mortality rate.
Deray Gilbert
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Abstract The use of amphotericin B limited by dose-dependent nephrotoxicity. Elevated creatinine associated with amphotericin B is not only a marker for renal dysfunction, but is also linked to an increase in hospital costs and a substantial risk for the use of haemodialysis and a higher mortality rate.
Deray Gilbert
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Applied Microbiology and Biotechnology, 2005
Invasive fungal infections are a major cause of morbidity and mortality in immunodeficient individuals (such as AIDS patients) and in transplant recipients or tumor patients undergoing immunosuppressive chemotherapy. Amphotericin B is one of the oldest, yet most efficient antimycotic agents. However, its usefulness is limited due to dose-dependent side-
Lemke, A. +2 more
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Invasive fungal infections are a major cause of morbidity and mortality in immunodeficient individuals (such as AIDS patients) and in transplant recipients or tumor patients undergoing immunosuppressive chemotherapy. Amphotericin B is one of the oldest, yet most efficient antimycotic agents. However, its usefulness is limited due to dose-dependent side-
Lemke, A. +2 more
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Pediatrics In Review, 1995
There are many circumstances in which pediatricians today may be involved in the care of patients at risk for systemic fungal infection. Among those at risk are children receiving chemotherapy for neoplastic disease, children infected with human immunodeficiency virus (HIV), and children undergoing immunosuppressive therapy for chronic illnesses or ...
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There are many circumstances in which pediatricians today may be involved in the care of patients at risk for systemic fungal infection. Among those at risk are children receiving chemotherapy for neoplastic disease, children infected with human immunodeficiency virus (HIV), and children undergoing immunosuppressive therapy for chronic illnesses or ...
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Amphotericin B and Coccidioidomycosis
Annals of the New York Academy of Sciences, 2007Abstract: Prior to the 1950s no effective therapy for coccidioidomycosis existed. The advent of amphotericin B ushered in the therapeutic era for coccidioidomycosis. Until this time amphotericin B and its lipid congeners have been regarded as the “gold standard” of therapy for severe pulmonary and disseminated coccidioidomycosis.
Royce H, Johnson, Hans E, Einstein
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Amphotericin B: an introduction
Journal of Antimicrobial Chemotherapy, 1991Amphotericin B has a broad spectrum of action that includes most of the major fungal pathogens of man. This drug binds to the membrane sterols of fungal cells, causing impairment of their barrier function and loss of cell constituents. Metabolic disruption and cell death are consequent upon membrane alterations.
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Drug Safety, 1990
The frequency of fungal infections is increasing. Amphotericin B remains the anti-fungal drug of choice for most systemic infections, but a limiting factor for its use is the development of nephrotoxicity. Amphotericin B-induced nephrotoxicity is manifested as azotaemia, renal tubular acidosis, impaired renal concentrating ability and electrolyte ...
R, Sabra, R A, Branch
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The frequency of fungal infections is increasing. Amphotericin B remains the anti-fungal drug of choice for most systemic infections, but a limiting factor for its use is the development of nephrotoxicity. Amphotericin B-induced nephrotoxicity is manifested as azotaemia, renal tubular acidosis, impaired renal concentrating ability and electrolyte ...
R, Sabra, R A, Branch
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Amphotericin B and Maduromycosis
Archives of Pediatrics & Adolescent Medicine, 1978Sir .—Let me react to the clinical memorandum on the treatment of Maduromycosis with amphotericin B by Hayden et al in theJournal(131:927, 1977). We would point out that our case, to which they refer in their third reference, also had "apparent remission," but recurred thereafter.
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