Results 201 to 210 of about 95,889 (290)

Small Molecule Targeting of Atypical p38 Protects Against Viral Infection

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Targeting host signaling pathways offers a complementary strategy to direct‐acting antivirals. Small‐molecule modulators of atypical p38 block Hepatitis C virus replication and also inhibit Human Cytomegalovirus. By disrupting virus‐induced p38 activation, these compounds suppress viral RNA replication and protein expression, highlighting atypical p38 ...
Fredejah T. Royer, Jeremy C. Burton, Johnathan Burns, Megan G. Lloyd, Reuben Onwe, Jennifer F. Moffat, Neil J. Grimsey   +6 more
wiley   +1 more source

Correction: Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B. [PDF]

J Orthop Surg Res
Frank FA, Krampitz B, Steiner J, Strathausen R, Morgenstern M, Clauss M, Kühn KD.   +6 more
europepmc   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, Volume 599, Issue 19, Page 2802-2816, October 2025.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Effects of fluconazole and amphotericin B in the control of cryptococcal pneumonia in vivo. [PDF]

AMB Express
Yu Z, Liu Z, Qian J, Qian Y.
europepmc   +1 more source

Immunoadjuvant activity of amphotericin B as displayed in mice infected with Candida albicans

, 1985
Francesco Bistoni, Anna Vecchiarelli, R. Mazzolla, Paolo Puccetti, P Marconi, Enrico Garaci   +5 more
openalex   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Role of liposomal amphotericin B in intensive care unit: an expert opinion paper. [PDF]

J Anesth Analg Crit Care
Bussini L, Bartoletti M, Bassetti M, Cortegiani A, De Pascale G, De Rosa FG, Falcone M, Giannella M, Girardis M, Grossi P, Mikulska M, Navalesi P, Pea F, Sanguinetti M, Tascini C, Viaggi B, Viale P.   +16 more
europepmc   +1 more source

ABSENCE OF CONGENITAL INFECTION AND TERATOGENESIS IN THREE CHILDREN BORN TO MOTHERS WITH BLASTOMYCOSIS AND TREATED WITH AMPHOTERICIN B DURING PREGNANCY

, 1987
Irwin Cohen
openalex   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against <i>Cryptococcus neoformans</i> H99. [PDF]

Antibiotics (Basel)
Sousa NSO, Almeida JDR, Rocha LSD, Moreira IMB, Fernandes FDS, Matsuura ABJ, Cruz KS, Lima ES, Souza ÉS, Frickmann H, Souza JVB.   +10 more
europepmc   +1 more source