Results 21 to 30 of about 98,354 (197)

Preventing or attenuating amphotericin B nephrotoxicity with dopamine receptor agonists: a literature review [PDF]

Trends in Pharmaceutical Sciences, 2015
Nephrotoxicity is generally considered as the most clinically significant and dose-limiting adverse reaction of amphotericin B. Currently, only the clinical effectiveness of salt loading and administering lipid formulations of amphotericin B have been ...
Iman Karimzadeh, Hossein Khalili, Mohammad Mahdi Sagheb   +2 more
doaj   +2 more sources

Using single-dose liposomal amphotericin B for cryptococcal meningitis induction therapy: nurse pearls and practical perspectives [version 1; peer review: 2 approved]

Wellcome Open Research
Background In Uganda where the burden of HIV-associated cryptococcal meningitis is high, conventional amphotericin B deoxycholate has been standard to manage patients with cryptococcal meningitis in research settings.
Richard Kwizera, Cynthia Ahimbisibwe, Jane Frances Ndyetukira, David B. Meya, Carol Namujju   +4 more
doaj   +1 more source

Evaluation of the efficacy, safety and economy of different amphotericin B formulations in invasive fungal disease: A retrospective cohort study

Precision Medication
Background: Fungal infections have emerged as an increasingly serious public health challenge globally. Four Formulations of amphotericin B are widely used in antifungal therapy.
Shuai Liu, Shizhao Yuan, Yan Liu, Shuoxian Jia, Yan Zhao, Ziyi Wang, Chunhua Zhou, Jing Yu   +7 more
doaj   +1 more source

Effects of Several Common Antifungal Drugs (Clotrimazole, Miconazole, Fluconazole) alone and in Combination with Amphotericin B on Candida Species Isolated from Chronic Candidal Vulvovaginitis [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background; Objective: Candidal vulvovaginitis occurs in female genital by the over growth of candida especially candida albicans. This infection may be resistant to therapy and occasionally becomes chronic.
Efate alsadat shojaei, Mehraban Falahati, Faride zaini, Parivash kord bache, Parvaneh rahimi moghadam, Mohammad reza aghamirian, Shima Nozari, Ayesheh Makhdoomi, Sekhavatv ameri, Sanam afshar moghadam   +9 more
doaj   +2 more sources

Using single-dose liposomal amphotericin B for cryptococcal meningitis induction therapy: nurse pearls and practical perspectives [version 2; peer review: 2 approved]

Wellcome Open Research
Background In Uganda where the burden of HIV-associated cryptococcal meningitis is high, conventional amphotericin B deoxycholate has been standard to manage patients with cryptococcal meningitis in research settings.
Richard Kwizera, Cynthia Ahimbisibwe, Jane Frances Ndyetukira, David B. Meya, Carol Namujju   +4 more
doaj   +1 more source

Case report: Reversible encephalopathy associated with liposomal amphotericin B in a patient with cryptococcal meningitis

Frontiers in Neurology, 2022
Liposomal amphotericin B (L-AMB) is an anti-fungus medicine that has fewer side effects than traditional amphotericin B (AMB). Neurotoxicity of L-AMB has rarely been observed, and only one case of leukoencephalopathy during intravenous L-AMB has been ...
Si Luo, Han Wen, Meihong Zhou, Chengsi Wu, Daojun Hong   +4 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Protective and antifungal properties of Nanodisk-Amphotericin B over commercially available Amphotericin B

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2017
Objective: Amphotericin B (AMB), a potent antifungal agent, has been employed as topical and systemic therapy for sinonasal fungal infections. A novel formulation of nanodisc (ND) containing super aggregated AMB (ND-AMB) for the treatment of fungal ...
Do-Yeon Cho, Kyle J. Hoffman, Gobind S. Gill, Dong-Jin Lim, Daniel Skinner, Calvin Mackey, Steven M. Rowe, Bradford A. Woodworth   +7 more
doaj   +1 more source

Bioinspired Bromination Enables Extensible, Strain‐Stiffening Resilin Peptide Scaffolds with Tunable Degradation

Advanced Functional Materials, EarlyView.
Bioinspired bromination of a resilin‐derived peptide enables the fabrication of electrospun nanofibrous scaffolds that uniquely combine strain‐stiffening elasticity, proteolytic stability, and antioxidant functionality. These brominated peptide–gelatin hybrids mimic the extensibility of natural elastomers, demonstrating tunable mechanical resilience ...
Elisa Marelli, Lorenzo Sori, Chiara Russo, Claudia Pigliacelli, Lorenza Draghi, Monica Soncini, Pierangelo Metrangolo   +6 more
wiley   +1 more source

Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis

Acta Dermato-Venereologica, 2022
The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis.
Michal Solomon, Shoshana Greenberger, Maya Milner, Felix Pavlotzky, Aviv Barzilai, Eli Schwartz, Noa Hadayer, Sharon Baum   +7 more
doaj   +1 more source