Results 221 to 230 of about 218,037 (308)

RETRACTED: Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Polyacrylamide hydrogel-immobilized <i>Escherichia coli</i> cell lysate for efficient removal and reduction in transformability of extracellular antibiotic resistance genes in water. [PDF]

Appl Environ Microbiol
Li H, Li F, Shi Y, Wang X, Wang X, Zheng G, Zhou L, Smets BF.   +7 more
europepmc   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, EarlyView.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Probable hindrance of visible colour due to excess biotin with CRISPR-dCas9-sgRNA lateral flow assay detection of HPV16 and HPV18: a negative finding. [PDF]

Sci Rep
Tamrakar VK, Sharma K, Singh P, Khan R, Bhargava A, Thakur P, Negi SS.   +6 more
europepmc   +1 more source

BacSafe: A Comprehensive Database for Integrated Assessment of Bacterial Biosafety

iMetaMed, EarlyView.
The substantial threats that bacterial contamination poses to healthcare and industrial production requires a comprehensive assessment of biosafety risks for each bacterial species. Here, we introduce BacSafe, a novel database that integrates diverse domains of biosafety knowledge and evaluates bacterial risk across both clinical and environmental ...
Ye Feng, Chengzhi Liu, Qian Liang, Lupeng Ma, Weilian Chen, Fanyuan Gu, Biao Tang, Zhijian Wang, Guoping Zhao, Huan Chen   +9 more
wiley   +1 more source

An amplicon-based tiled PCR scheme for the enrichment of avian metapneumovirus subtype B genomes prior to next generation sequencing. [PDF]

Front Cell Infect Microbiol
Álvarez-Narváez S, Suarez DL, Kapczynski DR.   +2 more
europepmc   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

<i>Brukina</i> in Focus: A Narrative Review on Metagenomic Approaches to Fermentation and Food Safety. [PDF]

Int J Microbiol
Kwarteng A, Amedorme D, Addy HPK, Amewu EKA, Osei-Poku P, Larbi A.   +5 more
europepmc   +1 more source

microeco 2: A comprehensive R package for downstream analysis of microbiome omics data

iMeta, EarlyView.
The current version 2.0 of the microeco package represents a substantial update compared to the previously published version. Key enhancements include the addition of new classes, integration of a broader suite of analytical methods, a comprehensive overhaul of the parameter system, improved connectivity between statistical analysis and visualization ...
Chi Liu, Xiangzhen Li, Felipe R. P. Mansoldo, Tong Chen, Fanzheng Meng, Ruixiang Tang, Siyu Zhou, Qinghua Yang, Ruixin Shao, Minjie Yao   +9 more
wiley   +1 more source

High-resolution melting analysis for rapid and cost-effective detection of unnatural base pairs. [PDF]

Biodes Res
van der Vlugt SEJ, Fros JJ, Martins Dos Santos VAP, Albada B, Asin-Garcia E.   +4 more
europepmc   +1 more source