Results 221 to 230 of about 165,809 (296)

BacSafe: A Comprehensive Database for Integrated Assessment of Bacterial Biosafety

iMetaMed, EarlyView.
The substantial threats that bacterial contamination poses to healthcare and industrial production requires a comprehensive assessment of biosafety risks for each bacterial species. Here, we introduce BacSafe, a novel database that integrates diverse domains of biosafety knowledge and evaluates bacterial risk across both clinical and environmental ...
Ye Feng, Chengzhi Liu, Qian Liang, Lupeng Ma, Weilian Chen, Fanyuan Gu, Biao Tang, Zhijian Wang, Guoping Zhao, Huan Chen   +9 more
wiley   +1 more source

Amplicon sequencing on the MinION platform v1

, 2020
openaire   +1 more source

Genomic characterization of a severe West Nile Virus transmission season using a single reaction amplicon sequencing approach. [PDF]

PLoS Negl Trop Dis
Freed S, Chandler S, Uhm S, Pella Z, Gurung D, Smith H, Dowdy T, Bartling AM, Butz A, Wiley MR, Broadhurst MJ, Stein S, McCutchen EL, Hamik J, Iwen PC, Downey N, Herzog KS, Fauver JR.   +17 more
europepmc   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

microeco 2: A comprehensive R package for downstream analysis of microbiome omics data

iMeta, EarlyView.
The current version 2.0 of the microeco package represents a substantial update compared to the previously published version. Key enhancements include the addition of new classes, integration of a broader suite of analytical methods, a comprehensive overhaul of the parameter system, improved connectivity between statistical analysis and visualization ...
Chi Liu, Xiangzhen Li, Felipe R. P. Mansoldo, Tong Chen, Fanzheng Meng, Ruixiang Tang, Siyu Zhou, Qinghua Yang, Ruixin Shao, Minjie Yao   +9 more
wiley   +1 more source

Identification of gut microbiota features of diarrheic calves using the full-length 16S rRNA gene amplicon sequencing and machine learning. [PDF]

Anim Microbiome
Hawkins J, Carpenter S, Joshi H, Bernard B, Brett J, McGee M, Smith T, Stone A, Hsu CY, Fan P.   +9 more
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

DNA and RNA-based amplicon sequencing of paired supragingival and dentin lesion plaque in children with severe early childhood caries. [PDF]

Int J Oral Sci
Naumann AA, Elmorr EM, Lamont EI, Hendrickson EL, Holmes T, Nelson TM, McLean JS, Kerns KA.   +7 more
europepmc   +1 more source

Early gut microbial and metabolic dysregulation with subclinical cardiac alterations in a nonhuman primate model of Rett syndrome

iMeta, EarlyView.
Longitudinal multi‐omics profiling of a nonhuman primate Rett syndrome (RTT) model reveals early systemic alterations. RTT monkeys exhibited postnatal growth retardation, intestinal structural abnormalities, and low‐grade systemic inflammation. Gut microbiome analysis showed delayed microbial maturation and age‐discordant dysbiosis, including altered ...
Ting Zhang, Xiaopeng Wang, Peng Li, Junyu Zhang, Wenjie Sun, Zhen Zhang, Yan Zhuo, Wenting Guo, Yongchang Chen   +8 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source