Results 211 to 220 of about 2,156,419 (333)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

LAMP-LFD: establishment and evaluation of a new diagnostic platform for SARS-CoV-2 rapid detection. [PDF]

Front Public Health
Diao Q, Tang S, Liu X, Li J, Zhou X, Chen Y, Zhang Q, Yang F.   +7 more
europepmc   +1 more source

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity

, 2019
Qingkun Liu, Emily M. Johnson, Rachel Lam, Qian Wang, Hong Bo Ye, Edward N. Wilson, Paras S. Minhas, Ling Liu, Michelle S. Swarovski, Stephanie Tran, Jing Wang, Swapnil Mehta, Xi Yang, Joshua D. Rabinowitz, Samuel Yang, Mehrdad Shamloo, Christoph Mueller, Michelle L. James, Katrin I. Andreasson   +18 more
openalex   +2 more sources

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Comparative analysis of diagnostic efficacy of loop-mediated isothermal amplification (LAMP) and CBNAAT in children with suspected tubercular meningitis: a cross-sectional study. [PDF]

BMJ Paediatr Open
Jain S, Dayal R, Kamal R, Singh D, Yadav N, Nayak M, Khan A, Gupta S, Lawaniya S, Awasthi AK.   +9 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Traitements audionumériques pour la guitare électrique amplifiée

Appareil, 2010
Benoît Courribet
doaj   +1 more source

The DNA damage response pathway is required for multiciliated cell differentiation. [PDF]

Curr Biol
Jewett CE, Holland AJ, Pearson CG.
europepmc   +1 more source

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With Advanced Malignancies

, 2019
Shumei Kato, Ryosuke Okamura, Manvita Mareboina, Suzanna Lee, Aaron M. Goodman, Sandip Pravin Patel, Paul T. Fanta, Richard B. Schwab, Peter Vu, Victoria M. Raymond, Richard B. Lanman, Jason K. Sicklick, Scott M. Lippman, Razelle Kurzrock   +13 more
openalex   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source