Results 61 to 70 of about 878,105 (387)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The development of unique optical materials that provide amplification and lasing in new wavelength ranges is a major scientific problem, the solution of which is becoming the basis for the emergence of new optical technologies, which are primarily ...
Sergey Alyshev+3 more
doaj +1 more source
Design of hysteresis circuits using differential amplifiers [PDF]
Design equations for hysteresis circuit are based on the following assumptions: amplifier input impedance is larger than source impedance; amplifier output impedance is less than load impedance; and amplifier switches state when differential input ...
Cooke, W. A.
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
This article proposes a voltage-to-frequency converter (VFC) design using unipolar metal-oxide thin film transistor (TFT) technology. The proposed VFC has an integrator and Schmitt trigger based structure.
Yuming Xu+9 more
doaj +1 more source
Fluid pressure amplifier and system [PDF]
A flueric beam-deflection amplifier and a method of controlling the same are described. Either a single or a series of cascaded fluid amplifier units are provided and each one of which may include the usual power nozzle, control nozzles, outlet passages ...
Garner, H. D., Hellbaum, R. F.
core +1 more source
Thulium-doped fiber amplifier for optical communications at 2µm
We report the realization of a thulium doped fiber amplifier designed for optical communications providing high gain (>35dB) and low noise figure (
Zhihong Li+5 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
A highly shielded and easy-integration antenna-in-package (AiP) configuration based on the rectangular hollow dielectric resonator antenna (DRA) is presented.
Sheng-Jie Guo+3 more
doaj +1 more source
Bio-isolated dc operational amplifier [PDF]
A bio-isolated dc operational amplifier is described for use in making bioelectrical measurements of a patient while providing isolation of the patient from electrical shocks. The circuit contains a first operational amplifier coupled to the patient with
Lee, R. D.
core +2 more sources