Results 61 to 70 of about 878,105 (387)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Bismuth-Doped Fiber Lasers and Amplifiers Operating from O- to U-Band: Current State of the Art and Outlook

open access: yesPhotonics
The development of unique optical materials that provide amplification and lasing in new wavelength ranges is a major scientific problem, the solution of which is becoming the basis for the emergence of new optical technologies, which are primarily ...
Sergey Alyshev   +3 more
doaj   +1 more source

Design of hysteresis circuits using differential amplifiers [PDF]

open access: yes, 1971
Design equations for hysteresis circuit are based on the following assumptions: amplifier input impedance is larger than source impedance; amplifier output impedance is less than load impedance; and amplifier switches state when differential input ...
Cooke, W. A.
core   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

An Integrator and Schmitt Trigger Based Voltage-to-Frequency Converter Using Unipolar Metal-Oxide Thin Film Transistors

open access: yesIEEE Journal of the Electron Devices Society, 2021
This article proposes a voltage-to-frequency converter (VFC) design using unipolar metal-oxide thin film transistor (TFT) technology. The proposed VFC has an integrator and Schmitt trigger based structure.
Yuming Xu   +9 more
doaj   +1 more source

Fluid pressure amplifier and system [PDF]

open access: yes, 1973
A flueric beam-deflection amplifier and a method of controlling the same are described. Either a single or a series of cascaded fluid amplifier units are provided and each one of which may include the usual power nozzle, control nozzles, outlet passages ...
Garner, H. D., Hellbaum, R. F.
core   +1 more source

Thulium-doped fiber amplifier for optical communications at 2µm

open access: yes2013 Optical Fiber Communication Conference and Exposition and the National Fiber Optic Engineers Conference (OFC/NFOEC), 2013
We report the realization of a thulium doped fiber amplifier designed for optical communications providing high gain (>35dB) and low noise figure (
Zhihong Li   +5 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

A Dielectric Resonator Antenna-in-Package Design and its Electromagnetic Interference Investigation on Amplifier

open access: yesIEEE Access, 2018
A highly shielded and easy-integration antenna-in-package (AiP) configuration based on the rectangular hollow dielectric resonator antenna (DRA) is presented.
Sheng-Jie Guo   +3 more
doaj   +1 more source

Bio-isolated dc operational amplifier [PDF]

open access: yes, 1974
A bio-isolated dc operational amplifier is described for use in making bioelectrical measurements of a patient while providing isolation of the patient from electrical shocks. The circuit contains a first operational amplifier coupled to the patient with
Lee, R. D.
core   +2 more sources

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