Results 71 to 80 of about 270,882 (298)
Design and Simulation of A New Proposed Single-Slope Integrating Analog-to- Digital Converter System Based on Non-Linear Amplifiers [PDF]
Engineering and Technology Journal, 2010 In this paper, a unipolar single-slope integrating analog-to-digitalconverter(ADC) is discussed, designed, and simulated, whereas, its conversiontime is less than that of the dual-slope integrating ADC.The proposed systemconsists of logarithmic amplifier,
Azzad B. Saeed
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Cladding-pumped Raman fiber with a W-type core designed for power scaling
, 2009 We design a cladding-pumped fiber Raman amplifier with a wavelength-filtering W-type core for the suppression of the 2nd-order Raman Stokes.
Nilsson, J., Ji, J., Codemard, C.A.
core +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Numerical analysis of four-wave mixing between 2 ps mode-locked laser pulses in a tensile-strained bulk SOA [PDF]
, 2007 A numerical model of four-wave mixing between 2-ps pulses in a tensile-strained bulk semiconductor optical amplifier is presented. The model utilizes a modified Schrodinger equation to model the pulse propagation. The Schrodinger equation parameters such
Reid, Douglas A. +7 more
core +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Effect of losses in an active device and harmonic network on the efficiency of Class F and inverse Class F power amplifiers [PDF]
, 2012 High frequency class F and inverse class F power amplifiers obtain high efficiency of dc to ac power conversion, by reducing the overlap of voltage and current waveforms at the output of the active device, to ensure that the power dissipated in the ...
Ghassemlooy, Zabih +5 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source