This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Enhancing Signal Purity in Josephson Structure Measurements
Superconducting Josephson structures play a significant role in quantum‐state engineering. Achieving high‐fidelity quantum state measurements in superconducting Josephson structures requires ultra‐low noise environments and robust signal purification ...
Ivan A. Nazhestkin +8 more
doaj +1 more source
SOLID-STATE COMPONENTS AND DEVICES OF TERAHERTZ ELECTRONIC TECHNOLOGY IN UKRAINE [PDF]
Subject and purpose. One of the main problems arising in the implementation of the terahertz range is associated with the need to provide the advanced equipment developed in this frequency band with effective electronic components.
N. F. Karushkin
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and Stability Analysis Techniques for Switching-Mode Nonlinear Circuits: Power Amplifiers and Oscillators [PDF]
A design technique for kW level switching mode power amplifiers is presented. Several push pull pairs, independently tuned to Class E/Fodd, are combined by a distributed active transformer.
Jeon, Sanggeun
core +1 more source
New Nanocrystalline Materials for Power Electronics Applications
New nanocrystalline materials for the applications in the power electronics systems are developed and tested.These materials are intended to be used in the magnetic circuits of switching-mode power supplies (SMPS).
Elemir Usak +3 more
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Slew Rate and Step Response of the Noninverting Structure with an Operational Amplifier
When a large-step input voltage is applied to an operational amplifier (OP AMP) input, the output waveform reises with a finite slope called the slex rate which is due to an amplifier input stage current limiting (Im) and because of a compensating ...
Josef Puncochar
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

