Results 51 to 60 of about 213,686 (292)

In-vivo evaluation of vitamin E loaded muscle void fillers for the provisional treatment of volumetric muscle loss

BMC Research Notes
Objective This study investigates the therapeutic potential of α-tocopherol (Vitamin E, VitE), delivered locally via a polyethylene glycol (PEG) hydrogel serving as a muscle void filler (MVF), for the acute treatment of volumetric muscle loss (VML) in a ...
Michael S. Valerio, Andrew R. Clark, Marissa N. Behun, Christopher L. Dearth, Stephen M. Goldman   +4 more
doaj   +1 more source

The musculotendinous interface: insights into development, injury, and recovery for military medical applications

Frontiers in Physiology
Musculoskeletal injuries (MSKIs) are a major cause of morbidity and lost duty time for military service members, impacting overall military readiness, with overuse injuries being particularly prevalent among them. Musculotendinous injuries, affecting the
Alex T. Adams, Alex T. Adams, Zachary G. Davis, Zachary G. Davis, Kyle F. Browder, Kyle F. Browder, Christopher L. Dearth, Christopher L. Dearth, Stephen M. Goldman, Stephen M. Goldman   +9 more
doaj   +1 more source

Patellar Tendon Morphology in Trans-tibial Amputees Utilizing a Prosthesis with a Patellar-tendon- Bearing Feature [PDF]

, 2019
A patellar-tendon-bearing (PTB) bar is a common design feature used in the socket of trans-tibial prostheses to place load on the pressure-tolerant tissue.
Bashford, Gregory, Chang, Yu-Jen, Harty, Michelle, Ho, Kai-Yu, Kellogg, Jessica, Lee, Szu-Ping, Teter, Kelly   +6 more
core   +4 more sources

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

A Two-Stage Approach Integrating Provisional Biomaterial-Mediated Stabilization Followed by a Definitive Treatment for Managing Volumetric Muscle Loss Injuries

Journal of Functional Biomaterials
Treatment of volumetric muscle loss (VML) faces challenges due to its unique pathobiology and lower priority in severe musculoskeletal injury management.
Andrew R. Clark, Jonathan Kulwatno, Sergey S. Kanovka, George J. Klarmann, Claudia E. Hernandez, Roman M. Natoli, Todd O. McKinley, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman   +9 more
doaj   +1 more source

Risk Factors for Lower Extremity Amputation in Diabetic Foot Ulcer Patients: A Case-Control Study

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2020
Introduction: Diabetes mellitus is a metabolic syndrome that is marked by higher blood glucose. The uncontrolled high blood glucose can lead to complication, such as diabetic foot.
Gusti Agung Ayu Ira Kencana Dewi, Sony Wibisono, I Putu Alit Pawana   +2 more
doaj   +1 more source

Characterization of initial ankle-foot prosthesis prescription patterns in U.S. Service members following unilateral transtibial amputation

Frontiers in Rehabilitation Sciences, 2023
IntroductionThe purpose of this study was to explore relationships between patient-specific characteristics and initial ankle-foot prosthesis prescription patterns among U.S.
Patrick G. Monaghan, Ashley D. Knight, Ashley D. Knight, Ashley D. Knight, Sarah A. Brinkerhoff, Kenneth D. Harrison, Christopher L. Dearth, Christopher L. Dearth, Brad D. Hendershot, Brad D. Hendershot, Brad D. Hendershot, JoEllen M. Sefton, Michael Zabala, Adan Vazquez, Adan Vazquez, David Shannon, David Crumbley, Jaimie A. Roper   +17 more
doaj   +1 more source

From satisfaction to expectation: The patient's perspective in lower limb prosthetic care [PDF]

, 2007
Neck pain is a common musculoskeletal complaint and a relationship with reduced work-related functional capacity is assumed. A validated instrument to test functional capacity of patients with neck pain is unavailable.
Geertzen, J.H.B., Hofstad, C.J., Postema, K., van der Linde, H., van Limbeek, J.   +4 more
core   +2 more sources

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Ontological theory for ontological engineering: Biomedical systems information integration [PDF]

, 2004
Software application ontologies have the potential to become the keystone in state-of-the-art information management techniques. It is expected that these ontologies will support the sort of reasoning power required to navigate large and complex ...
Ceusters, Werner, Fielding, James M., Simon, Jonathan, Smith, Barry   +3 more
core   +1 more source