Results 61 to 70 of about 450,311 (295)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Methicillin Resistant Staphylococcus aureus: Molecular Mechanisms Underlying Drug Resistance Development and Novel Strategies to Combat

Infection and Drug Resistance, 2023
Assefa Asnakew Abebe,1,2 Alemayehu Godana Birhanu1 1Department of Molecular Biology, Institute of Biotechnology, Addis Ababa University, Addis Ababa, Ethiopia; 2Department of Medical laboratory Sciences, Institute of Health, Bule Hora University, Bule ...
Abebe AA, Birhanu AG
doaj  

Lentic and effluent water of Delhi-NCR: a reservoir of multidrug-resistant bacteria harbouring blaCTX-M, blaTEM and blaSHV type ESBL genes

Journal of Water and Health, 2021
Antimicrobial resistance is not restricted to clinics but also spreading fast in the aquatic environment. This study focused on the prevalence and diversity of extended-spectrum β-lactamase (ESBL) genes among bacteria from lentic and effluent water in ...
Asghar Ali, Insha Sultan, Aftab Hossain Mondal, Mohammad Tahir Siddiqui, Firdoos Ahmad Gogry, Qazi Mohd. Rizwanul Haq   +5 more
doaj   +1 more source

Covariant density functional theory for antimagnetic rotation

, 2012
Following the previous letter on the first microscopic description of the antimagnetic rotation (AMR) in 105Cd, a systematic investigation and detailed analysis for the AMR band in the frame-work of tilted axis cranking (TAC) model based on covariant ...
A. Bohr, H. Z. Liang, J. Meng, J. Meng, J. Peng, P. Ring, P. Ring, P. W. Zhao, S. Frauendorf, S. Frauendorf, S. Frauendorf   +10 more
core   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

The Implementation Of Autonomous Mobile Robots In Industrial Brownfield Environments - A literature review

Proceedings of the Conference on Production Systems and Logistics
With the increasing automation of production and logistics systems, the demand for autonomous mobile robots (AMRs) has risen significantly in recent years. They enable an efficient and flexible organization to optimize material flow.
Benkhoff, Lana, Straub, Natalia, Thayaparan, Thanushan, Haack, Charlotte, Herberger, David, Hübner, Marco   +5 more
doaj   +1 more source

Robust Subgraph Generation Improves Abstract Meaning Representation Parsing [PDF]

, 2015
The Abstract Meaning Representation (AMR) is a representation for open-domain rich semantics, with potential use in fields like event extraction and machine translation.
Angeli, Gabor, Manning, Christopher, Werling, Keenon   +2 more
core  

Highly anisotropic interlayer magnetoresistance in ZrSiS nodal-line Dirac semimetal

, 2019
We instigate the angle-dependent magnetoresistance (AMR) of the layered nodal-line Dirac semimetal ZrSiS for the in-plane and out-of-plane current directions.
Biliskov, N., Eguchi, G., Kimura, A., Kokanovic, I., Novak, M., Orbanic, F., Osada, T., Paschen, S., Sato, M., Uchida, K., Wang, X. X., Wu, Q. S., Yazyev, O. V., Zhang, S. N.   +13 more
core   +2 more sources

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

An In vitro Investigation of the Potential Synergistic Effect of 3-Hydrazinoquinoxaline-2-Thiol and Thymoquinone’s against Methicillin Resistant Staphylococcus aureus (MRSA)

Journal of Pure and Applied Microbiology
Bacterial infections continue to pose a significant global health threat, further intensified by the increasing prevalence of antibiotic resistance. Methicillin-resistant Staphylococcus aureus (MRSA) poses significant threats, especially in healthcare ...
Karem Ibrahem, Wafaa Alhazmi, Hanouf A. Niyazi, Hatoon A. Niyazi, Bandar Saleh, Tariq Ekhmimi, Jawahir A. Mokhtar, Dalya Attallah, Mohammed Bazuhair, Khalil Alkuwaity, Ahmad Sait, Mohammed Mufrrih, Mazen Ismail, Yousef Almoghrabi, Hussam Daghistani, Ohood Alharbi, Hisham Altayb, Abdelbagi Alfadil   +17 more
doaj   +1 more source