Results 71 to 80 of about 155,071 (257)
Advanced Science, EarlyView.Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair +3 more
wiley +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics
Advanced Science, EarlyView.This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka +3 more
wiley +1 more source
Postępy MikrobiologiiNeisseria gonorrhoeae (gonococcus) is a human pathogen, the aetiological agent of gonorrhoea, which is the second most common bacterial sexually transmitted disease (STD) in the world. The structure of N. gonorrhoeae cell wall is typical of Gram-negative
Białecka Joanna +2 more
doaj +1 more source
Towards AMR Simulations of Galaxy Formation [PDF]
, 2010 Numerical simulations present a fundamental building block of our modern theoretical understanding of the Universe. As such the work in this thesis is primarily concerned with understanding fundamental differences that lie between the different ...
MITCHELL, NIGEL,LEWIS +1 more
core
XL-AMR: Enabling Cross-Lingual AMR Parsing with Transfer Learning Techniques [PDF]
, 2020 Meaning Representation (AMR) is a popular formalism of natural language that represents the meaning of a sentence as a semantic graph. It is agnostic about how to derive meanings from strings and for this reason it lends itself well to the encoding of ...
Tripodi, Rocco +5 more
core +1 more source
Advanced Science, EarlyView.A temperature‐driven magnetic anisotropy crossover is revealed in the Dirac kagome magnet Fe3Ge with a distorted kagome lattice. The transition from easy‐plane to easy‐axis magnetic anisotropy stabilizes robust Bloch‐type skyrmions over an exceptionally wide temperature window of 375–650 K.
Yalei Huang +15 more
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Postępy MikrobiologiiNeisseria gonorrhoeae is an aetiological agent of gonorrhoea, which is a sexually transmitted disease (STD), a public health challenge worldwide. Gonorrhoea is undoubtedly a serious health risk, especially for women, due to its often asymptomatic course ...
Białecka Joanna +2 more
doaj +1 more source
cghss/AMR-WASH-AMPEID: AMPEID_WASH_AMR
<p>Data and script for the AMR/WASH project</p ...
Ciara Weets
core +1 more source