Results 151 to 160 of about 197,077 (309)

Immune‐related adverse events in the treatment of Hodgkin lymphoma with immune checkpoint inhibitors

British Journal of Haematology, EarlyView.
Summary Immune checkpoint inhibitors (ICIs) have shown to be effective in the treatment of Hodgkin lymphoma (HL). ICI treatment is associated with the occurrence of a series of immune‐related adverse events (irAEs). We conducted an ambispective observational study on 96 patients with relapsed/refractory HL treated with ICIs to determine the incidence ...
Lisa Argnani, Vittorio Stefoni, Beatrice Casadei, Carla Pelusi, Valentina Lo Preiato, Uberto Pagotto, Anna Buganè, Cinzia Pellegrini, Alessandro Broccoli, Pier Luigi Zinzani   +9 more
wiley   +1 more source

LC-HESI-MS/MS Profiling and Evaluation of Antioxidant, Anti-Inflammatory, Anti-α-Amylase, and Anti-Acetylcholinesterase Activities of Rhus tripartitum L. Leaf Extract: In Vitro and In Silico Studies. [PDF]

Chem Biodivers
Ameur RB, Rekik I, Hamdaoui N, Soltani S, Téné N, Treilhou M, Saoudi M, Allouche N.   +7 more
europepmc   +1 more source

Occupational Contact Urticaria, Protein Contact Dermatitis and Concomitant Airway Diseases in the Finnish Register of Occupational Diseases in 2005–2020: Main Causes and Occupations at Risk

Contact Dermatitis, EarlyView.
This Finnish registry study shows that concomitant occupational asthma and rhinitis are common in patients with occupational contact urticaria or protein contact dermatitis, often sharing the same exposure. When evaluating occupational immediate allergy, both skin and airway symptoms should be considered.
Ville Ojanen, Liisa Airaksinen, Hille Suojalehto, Kirsi Koskela, Maria Pesonen   +4 more
wiley   +1 more source

Diagnostic Utility of Urinary Amylase in Acute Pancreatitis: A Systematic Review. [PDF]

Cureus
Ullah U, Chishti SSA, Junaid A, Sarwar M.   +3 more
europepmc   +1 more source

Effectiveness and Safety of Evogliptin in Patients With Type 2 Diabetes Mellitus: A Multicenter, Prospective, Observational Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Evogliptin, a dipeptidyl peptidase‐4 inhibitor with a glucose‐dependent mechanism of action, is widely used as a monotherapy or in combination with other agents. However, observational studies in routine clinical settings remain limited.
Jun Hwa Hong, Sung Hoon Yu, Ki‐Hyun Baek, JaeMyung Yu, Seung Jin Lee, Hyung‐Wook Kim, Kang Seo Park, Jung Han Kim, KyungWan Min, Yong Hwan Lee, Koon Soon Kim, Min Soo Song, Ji Hoon Kim, Jie‐Eun Lee, Jong Chul Won   +14 more
wiley   +1 more source

Management of an uncommon complication using botulinum toxin type A following prosthetic laryngoplasty

Equine Veterinary Education, EarlyView.
Summary An uncommon complication following prosthetic laryngoplasty was reported in a 4‐year‐old Andalusian mare. The mare was presented with a previously diagnosed left‐sided recurrent laryngeal neuropathy, after initial evaluation the mare underwent ventriculocordectomy and prosthetic laryngoplasty.
J. L. Sanclemente, D. S. Larriva, C. A. Ragle   +2 more
wiley   +1 more source

Modifiable Factors Affecting the Postprandial Glycemic Response. [PDF]

J Diabetes Sci Technol
Wu Y, McLaughlin T, Gorgani S, Scheideman AF, Shao MM, Hislop BD, Hoang K, Perelman D, McGinity C, Rodgar M, Park H, Wang T, Mayer C, DuNova A, Ayers A, Ho C, Ræder H, Klonoff DC, Snyder MP.   +18 more
europepmc   +1 more source

Microplastic Impacts on Seafood: A Global Synthesis of Experimental Findings

Fish and Fisheries, EarlyView.
ABSTRACT Plastic pollution is a growing global concern, with plastic and microplastic particles now widespread in aquatic environments. Microplastics are frequently ingested by marine organisms, including commercially important seafood species. Ingestion can lead to a range of biological effects, influenced by the size, type and quantity of plastic, as
Nina Wootton, Patrick Reis‐Santos, Rhiannon A. Van Eck, Isaac Duke, Bronwyn M. Gillanders   +4 more
wiley   +1 more source

Unveiling the Antidiabetic Potential of <i>Parmentiera edulis</i>: From Polyphenols to Molecular Interaction. [PDF]

Metabolites
Emus Medina A, Santos-Ballardo CL, Castro-Tamayo CB, Castillo-López RI, Angulo-Escalante MA, Portillo-Loera JJ, Heredia JB.   +6 more
europepmc   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source