Results 11 to 20 of about 1,279,543 (154)
The Journal of Headache and PainBackground The upper cervical dorsal root ganglia (DRG) are important for the transmission of sensory information associated with the back of the head and neck, contributing to head pain.
Tayla A. Rees +5 more
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Recent Studies on the Effectiveness and Safety of Anti-Obesity Medications: A Scoping Review [PDF]
Diabetes, Metabolic Syndrome and ObesityIrma Melyani Puspitasari,1,2,* Dimas Setyadi Putra,2,* Alifa Nisa Deliyana,3 Nurqisthi Iqlima Adiputri,3 Lily Indriani Octovia,4 Sekar Ayu Paramita,5 Rano Kurnia Sinuraya1,2,*1Department of Pharmacology and Clinical Pharmacy ...
Puspitasari IM +6 more
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History of current non-insulin medications for diabetes mellitus [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2012 This article is a brief review of the current non-insulin agents for diabetes mellitus in the United States, namely, sulfonylureas, biguanides, thiazolidinediones, meglitinides, α-glucosidase inhibitors, glucacon-like peptide-1 receptor agonists ...
Celeste C. L. Quianzon, Issam E. Cheikh
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Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease
Molecular Metabolism, 2021 Background: Glucagon-like peptide-1 receptor (GLP-1R) agonists are approved to treat type 2 diabetes and obesity. They elicit robust improvements in glycemic control and weight loss, combined with cardioprotection in individuals at risk of or with pre ...
Laurie L. Baggio, Daniel J. Drucker
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CiD agonists: Circular DNA-based agonists for the fine-tuning of receptor signaling [PDF]
, 2022 Receptor dimerization geometry plays a significant role in signal transduction induced by growth factors and cytokines. A chemical strategy capable of controlling dimerization geometry provides a means for studying receptor activation mechanisms and ...
Momoko , Akiyama +4 more
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Biomolecules, 2021 The calcitonin and amylin receptors (CTR and AMY receptors) are the drug targets for osteoporosis and diabetes treatment, respectively. Salmon calcitonin (sCT) and pramlintide were developed as peptide drugs that activate these receptors.
Sangmin Lee
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Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat
Frontiers in Endocrinology, 2021 The hormones amylin and calcitonin interact with receptors within the same family to exert their effects on the human organism. Calcitonin, derived from thyroid C cells, is known for its inhibitory effect on osteoclasts.
David S. Mathiesen +10 more
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Frontiers in Psychiatry, 2023 Alcohol use disorder (AUD) contributes substantially to global morbidity and mortality. Given the heterogenicity of this brain disease, available pharmacological treatments only display efficacy in sub-set of individuals.
Maximilian Tufvesson-Alm +2 more
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Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships [PDF]
, 2008 Potent and selective histamine H2 receptor (H2R) agonists are valuable pharmacological tools and might be of therapeutic value as drugs, for example in the treatment of severe congestive heart failure.
Kraus, Anja
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An Overview of Appetite-Regulatory Peptides in Addiction Processes; From Bench to Bed Side
Frontiers in Neuroscience, 2021 There is a substantial need for new pharmacological treatments of addiction, and appetite-regulatory peptides are implied as possible candidates. Appetite regulation is complex and involves anorexigenic hormones such as glucagon-like peptide-1 (GLP-1 ...
Olesya T. Shevchouk +2 more
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