Results 161 to 170 of about 2,028,198 (315)

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

Angewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Wang, Hegne Pupart, Xun Sun, Jan Gui‐Hyon Dreiser, Peep Palumaa, Qinghua Liao, Matthias Krack, Jinghui Luo   +9 more
wiley   +1 more source

A Balancing Act: Amyloid-β, Tau, and Excitation-Inhibition in Alzheimer's Disease. [PDF]

Epilepsy Curr
Silva-Pérez M, Chin J.
europepmc   +1 more source

Author response: A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

Hyo Jun Kwon, Devi Santhosh, Zhen Huang
openalex   +1 more source

A novel antagonistic role of natural compound icariin on neurotoxicity of amyloid β peptide

, 2015
Jianhui Liu, Fei Yin, Zixuan Liu, Yonglan Zhang   +3 more
openalex   +1 more source

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Nature Immunology, 2008
A. Halle, V. Hornung, G. Petzold, C. Stewart, Brian G. Monks, T. Reinheckel, K. Fitzgerald, E. Latz, K. Moore, D. Golenbock   +9 more
semanticscholar   +1 more source

Amyloid-β and Tau in Alzheimer's disease: pathogenesis, mechanisms, and interplay. [PDF]

Cell Death Dis
Abdulkhaliq AA, Kim B, Almoghrabi YM, Khan J, Ajoolabady A, Ren J, Bahijri S, Tuomilehto J, Borai A, Pratico D.   +9 more
europepmc   +1 more source

Amyloid β-Peptide Possesses a Transforming Growth Factor-β Activity [PDF]

, 1998
Shuan Shian Huang, Franklin W. Huang, Jan Xu, Shawei Chen, Chung Y. Hsu, Jung San Huang   +5 more
openalex   +1 more source

Fulminant Amyloid β-Related Angiitis With Herniation and Rapid Response to Tocilizumab: A Case Report. [PDF]

Neurol Neuroimmunol Neuroinflamm
Nguyen JV, Byrne EM, Yuan S, Bhattacharyya S, Kozberg MG, Lukacs M, Bilodeau PA.   +6 more
europepmc   +1 more source

O‐Terphenyl‐basierte Familie konjugierter Makrozyklen: Selektive Erkennung von Phenylalanin im Wasser und Interaktion mit Insulin

Angewandte Chemie, EarlyView.
Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Structural defects in amyloid-β fibrils drive secondary nucleation. [PDF]

Nat Commun
Hu J, Scheidt T, Thacker D, Axell E, Stemme E, Łapińska U, Wennmalm S, Meisl G, Curk S, Andreasen M, Vendruscolo M, Arosio P, Šarić A, Schmit JD, Knowles TPJ, Sparr E, Linse S, Michaels TCT, Dear AJ.   +18 more
europepmc   +1 more source