Results 171 to 180 of about 2,028,198 (315)
Angewandte Chemie International Edition, EarlyView.Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann +9 more
wiley +1 more source
Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy [PDF]
, 2016 Liang Wang +10 more
openalex +1 more source
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Nature Neuroscience, 2010 J. Palop, L. Mucke
semanticscholar +1 more source
Angewandte Chemie International Edition, EarlyView.This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule +5 more
wiley +1 more source
Animal Research and One Health, EarlyView.Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao +12 more
wiley +1 more source
Binding of amyloid β-peptide to ganglioside micelles is dependent on histidine-13 [PDF]
, 2006 Michael P. Williamson +3 more
openalex +1 more source