Results 201 to 210 of about 2,028,198 (315)

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Discovery of NIRF theranostic probes targeting amyloid-β and cholinesterases in Alzheimer's disease models. [PDF]

Nat Commun
Rai H, Singh R, Shankar G, Rai S, Kumar P, Nilakhe AS, Singh N, Bhadoria P, Singh G, Ramanathan V, Gupta S, Krishnamurthy S, Srikrishna S, Kumar S, Modi G.   +14 more
europepmc   +1 more source

Characterization of the acetylcholine-reducing effect of the amyloid-β peptide in mouse SN56 cells

, 1997
Ward A. Pedersen, Jan Krzysztof Blusztajn   +1 more
openalex   +1 more source

Cu(I) Is a Game Changer in the Arrest of Cu(Aβ)‐Induced ROS Production in the Presence of Competing Zn(II) Ions

Chemistry – A European Journal, EarlyView.
ABSTRACT ROS production due to Cu(amyloid‐β) redox cycling is proposed to contribute to the oxidative stress observed in Alzheimer's disease brains. We previously reported on a nitrogen and sulfur‐containing ligand, L, able to arrest Cu(Aβ)‐induced ROS production [Chem. Eur. J. 2023, 29,].
Marielle Drommi, Kyangwi Patrick Malikidogo, Elena Atrián‐Blasco, Charlène Esmieu, Christelle Hureau   +4 more
wiley   +1 more source

Data-driven modeling of amyloid-β targeted antibodies for Alzheimer's disease. [PDF]

NPJ Syst Biol Appl
Rabiei K, Petrella JR, Lenhart S, Liu C, Hao W, Alzheimer Disease Neuroimaging Initiative.   +5 more
europepmc   +1 more source

Racemic N1-Norphenserine and Its Enantiomers: Unpredicted Inhibition of Human Acetyl- and Butyrylcholinesterase and β-Amyloid Precursor Protein in vitro

, 2003
Nigel H. Greig, Qian‐sheng Yu, Weiming Luo, Harold W. Holloway, Tada Utsuki, Tracy Ann Perry, Debomoy K. Lahiri, Arnold Brossi   +7 more
openalex   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Neuroprotective role of pioglitazone in reversing hippocampal insulin resistance in Amyloid-β fibrils induced animal model of Alzheimer's disease

, 2019
Syed Obaidur Rahman, Suhel Parvez, Bibhu Prasad Panda, Abul Kalam Najmi   +3 more
openalex   +1 more source

Mutagenic exploration of the cross‐seeding and fibrillation propensity of Alzheimer's β‐amyloid peptide variants [PDF]

, 2006
Alexander Peim, Peter Hortschansky, Tony Christopeit, Volker Schroeckh, Walter Richter, Marcus Fändrich   +5 more
openalex   +1 more source