Results 211 to 220 of about 2,028,198 (315)

Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis

Alzheimer's & Dementia, 2017
Vitaliy Ovod, Kara N Ramsey, K. Mawuenyega, J. Bollinger, Terry J. Hicks, Theresa Schneider, Melissa Sullivan, K. Paumier, David M. Holtzman, J. Morris, T. Benzinger, Anne M. Fagan, Bruce W. Patterson, R. Bateman   +13 more
semanticscholar   +1 more source

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

Adiponectin deficiency drives cerebrovascular dysfunction and synergizes with amyloid-β to exacerbate alzheimer's pathology. [PDF]

Alzheimers Res Ther
Zou W, Yick LW, Kwan JS, Zhang Z, Xue H, Chan KH.   +5 more
europepmc   +1 more source

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

Clinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz, Eric Farber‐Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J. Garrett, Samuel M. Rubinstein, Michael G. Fradley, Mohammed E. Alomar, Danny DeAvila, Kenneth H Shain, R. Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C. Baz, Yan Gong   +15 more
wiley   +1 more source

Contribution of local amyloid-β and tau burden to hypometabolism in autosomal-dominant Alzheimer's disease. [PDF]

Brain Commun
Tristão-Pereira C, Langella S, Baena A, Londono N, Sanchez JS, Martinez L, Alvarez S, Vidal M, Aguillon D, Su Y, Protas H, Properzi MJ, Malotaux V, He B, Giudicessi A, Reiman EM, Hanseeuw BJ, Quiroz YT.   +17 more
europepmc   +1 more source

Chronic Intermittent Hypoxia/Reoxygenation Facilitate Amyloid-β Generation in Mice

, 2013
Satomi Shiota, Hidenori Takekawa, Shin‐ei Matsumoto, Kazuya Takeda, Fariz Nurwidya, Yasuko Yoshioka, Fumiyuki Takahashi, Nobutaka Hattori, Takeshi Tabira, Hideki Mochizuki, Kazuhisa Takahashi   +10 more
openalex   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Amyloid β-Cholesterol Interplay: Removal of Cholesterol From the Membranes to Catalyze Aggregation and Amyloid Pathology. [PDF]

J Neurochem
Baral R, van Deventer R, Lyubchenko YL.
europepmc   +1 more source

Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

, 2019
Victor Bodart‐Santos, Luiza Carvalho, Mariana Araya de Godoy, André F. Batista, Leonardo Saraiva, Luize G. Lima, Carla Andreia Abreu, Fernanda G. De Felice, Antônio Galina, Rosalia Méndez‐Otero, Sérgio T. Ferreira   +10 more
openalex   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source